Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute acute lymphocytic leukemia (ALL), myeloid leukemia (AML), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma. It is given by injection into a vein, under the skin, or into the cerebrospinal fluid.
- Name: Cytarabine
- Chemical Names: Cytarabine; 147-94-4; Cytosine arabinoside; Ara-C; Arabinocytidine; Cytosar; Tarabine; Alexan; Udicil; Cytosar-U; Aracytin
- Molecular Formula: C9H13N3O5
- Molecular Weight: 243.219 g/mol
- IUPAC Name: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- CAS Number: 147-94-4
- Physical Description: It is a colorless crystals.
- Color: White to off-white crystalline powder
- Odor: Odorless
- Melting Point: 212 - 213 °C
- Solubility: Soluble in water
- Decomposition: When heated to decomp it emits toxic fumes of /nitrogen oxides/.
- Drug Indication: Used for the treatment of acute non-lymphocytic leukemia, acute lymphocytic leukemia and blast phase of chronic myelocytic leukemia.
- Drug Classes: Antineoplastic Agents