Atovaquone

Product Description

We are offering high quality of Atovaquone. We are known for manufacturing,exporting,

distributing, trading and supplying Atovaquone  in Gujarat, India. Further, this is safely

packaged by our professionals in diverse packaging options that maintain its purity and

effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier

of Atovaquone in Gujarat. India. Shreeji Pharma International manufacturing & supplying all

products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier

of Atovaquone Nowadays Shreeji Pharma International is one of the leading manufacturer

and exporter, who is manufacturing Atovaquone as well as Intermediates of Atovaquone.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the

Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Atovaquone to countries like Gulf Countries,

South East Asia countries, African Countries, CIS Countries, LATAMcountries, Central

American Countries and in European countries.

Atovaquone Powder is an antiprotozoal and antimicrobial medication primarily used in the treatment and prevention of certain infections, including malaria and pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii. It is an oral medication that is often combined with other drugs, such as proguanil, to treat malaria. Heres a detailed description of Atovaquone Powder:

Chemical Structure and Composition:

Name: Atovaquone

Chemical Formula: C22H19ClO3

Molecular Weight: 365.8 g/mol

CAS Number: 84001-47-4

IUPAC Name: 2-(4-chlorophenyl)-6-(hydroxymethyl)-3(2H)-pyridazinone

Structure: Atovaquone is a hydroxymethyl pyridazinone compound with a chlorophenyl group. It has a lipophilic nature, allowing it to accumulate in tissues where parasites reside, especially in the mitochondria of protozoal cells.

Physical Properties:

Appearance: Atovaquone powder is a yellow to off-white crystalline powder.

Solubility: It is poorly soluble in water but soluble in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, and acetone.

Melting Point: Approximately 192C.

Stability: Atovaquone is relatively stable when stored in dry, cool conditions, though it can degrade in the presence of excessive moisture or heat.

Indications and Uses:

Malaria: Atovaquone is often used as part of a combination therapy with proguanil for the treatment and prevention of Plasmodium falciparum malaria, especially in areas with drug-resistant strains.

Pneumocystis Pneumonia (PCP): It is used in the treatment and prevention of Pneumocystis jirovecii pneumonia, especially in patients with compromised immune systems, such as those with HIV/AIDS.

Toxoplasmosis: It may also be used as part of a regimen for treating Toxoplasma gondii infections in immunocompromised individuals.

Side Effects:Common Side Effects:Gastrointestinal issues: Nausea, vomiting, abdominal pain, and diarrhea.

Headache.,Rash or skin reactions.

Serious Side Effects:

Liver toxicity: Elevated liver enzymes, jaundice, and liver dysfunction.

Pulmonary issues: Shortness of breath, cough, or chest pain (rare).

Severe allergic reactions: Anaphylaxis or hypersensitivity reactions (rare).

Other effects: There may be an increased risk of drug interactions when combined with other medications, such as rifampin, phenytoin, or carbamazepine, which can affect Atovaquones effectiveness.