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Glibenclamide

2800.0 INR/Kilograms

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Product Details:

Shelf Life 3 Years
Smell No Smell
Taste Odorless
Loss on Drying not more than 0.5%
Structural Formula CH3 | Cl-C6H4-SO2-N-C(=O)-N-C5H4SO2 | (Cyclohexylmethylthio group)
Particle Size 50 to 150 micrometers
Storage Room Temperature
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Glibenclamide Price And Quantity

Price Range 25.00 - 50.00 INR/Kilograms
Price 2800.0 INR/Kilograms
Minimum Order Quantity 25 Kilograms

Glibenclamide Product Specifications

Physical Form Powder
Melting Point 168 171 C
Purity(%) not less than 98%
Molecular Weight 494.01 Grams (g)
EINECS No 233-456-9
Solubility It is slightly soluble in water
Heavy Metal (%) Not more than 10 ppm
Molecular Formula C23H28ClN3O5S
Usage Glibenclamide (also known as Glyburide) is primarily used in the management of type 2 diabetes. Here are its main uses: Type 2 Diabetes Management: It is used to lower blood sugar levels in people with type 2 diabetes by stimulating the release of insulin from the pancreas. This helps improve the body's ability to utilize glucose. Combination Therapy: Glibenclamide can be used alone or in combination with other antidiabetic medications, such as metformin, when blood sugar levels are not adequately controlled with a single medication. Hyperglycemia: It helps in controlling hyperglycemia (high blood sugar) by increasing insulin sensitivity and decreasing hepatic glucose production. Note: It is generally not recommended for use in people with type 1 diabetes or diabetic ketoacidosis due to its mechanism of action, which requires functioning pancreatic beta cells to release insulin. As with all medications, it should be taken under the guidance of a healthcare professional to ensure proper dosage and monitoring of blood sugar levels
Type Pharmaceutical Intermediates
Ph Level 4.5 to 7
Chemical Name 1-[[[4-(Cyclohexylmethylthio)-3-methylphenyl] sulfonyl]amino]-3-pyridinesulfonyl]urea.
HS Code 29242190
CAS No 10238-21-8
Appearance White or almost white crystalline powder
Shelf Life 3 Years
Taste Odorless
Smell No Smell
Loss on Drying not more than 0.5%
Particle Size 50 to 150 micrometers
Structural Formula CH3 | Cl-C6H4-SO2-N-C(=O)-N-C5H4SO2 | (Cyclohexylmethylthio group)
Medicine Name Glibenclamide
Storage Room Temperature
Grade Medicine Grade

Glibenclamide Trade Information

FOB Port mumbai
Payment Terms Cash Against Delivery (CAD), Days after Acceptance (DA), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)
Supply Ability 1000 Kilograms Per Day
Delivery Time 7 Days
Sample Available Yes
Sample Policy Free samples are available
Packaging Details drum or bag packing
Main Export Market(s) Asia, Australia, Central America, North America, Africa, South America, Eastern Europe, Western Europe, Middle East
Certifications WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

Product Description

Glibenclamide in the offering is of high quality and highly demanded for its purity and effectiveness. It is safely packaged and supplied within India as well as outside India. Diabetes mellitus type two is treated with Glibenclamide, also called glyburide. Diet and exercise are recommended in conjunction with this supplement. It may be combined with other antidiabetic medications. It should not be used by itself for diabetes mellitus type 1. Your pancreas produces more insulin when you take glibenclamide. Sugar levels in your blood are reduced by this.

Technical Specifications:

CAS ID: 10238-21-8
Formula: C23H28ClN3O5S
Molar mass: 494.004 g/mol
Synonyms: Glyburide
melting point: 169 ÂC
Boiling point : 705.7Â70.0 ÂC at 760 mmHg
Purity: ‰ 99.0%

How does it work:

Glibenclamide increases insulin production in the pancreas. Your blood sugar is reduced as a result.
The drug acts by inhibiting the ATP-sensitive K+ channels, which results in insulin secretion and depolarization of cells. Additionally, the drug can have extrapancreatic effects on the liver, heart muscles, skeletal muscles, and smooth muscles.

Applications Or where it is used:

Type 2 diabetes mellitus is treated with glibenclamide. When combined with nutrition and exercise, this antidiabetic medication controls blood sugar levels in adults with type 2 diabetes. The pancreas releases more insulin to lower blood glucose levels.

How to use:

Your doctor usually recommends that you take this medication once a day with breakfast or with the first meal you eat that day. The patient may be advised to take this drug twice a day, especially those taking higher doses. Dosages are determined by your health conditions and treatment response. If you already take another diabetes medication, your doctor will tell you how to stop it and begin glyburide. Take glyburide four hours before colesevelam if you are also taking it.

Dosage of usage:

Type 2 Diabetes Mellitus
Regular tablets:
Initial: 2.5-5 mg PO qDay
Maintenance: 1.25-20 mg PO qDay or q12hr
Do not exceed 20 mg/day
Administer q12hr for doses >10 mg/day
Transferring from insulin therapy to glyburide
-Current insulin dose <20 units: Stop taking insulin and start glyburide dose at 2.5-5 mg/day (regular) or 1.5-3 mg/day (micronized)
-Current insulin dose 20-40 units: Stop taking insulin and start glyburide dose at 5 mg/day (regular) or 3 mg/day (micronized)

Side effects:

Weight gain, nausea, heartburn, and stomach fullness are possible side effects. Tell your doctor or pharmacist if you experience any of these effects. Consult a doctor immediately if anyone experiences any serious side effects, such as easy bleeding/bruising, dark urine, stomach pain, yellowing eyes/skin, unusual tiredness, unusual weight gain, mood swings, seizures, etc.

Warnings and precautions while using this product:

Glyburide must not be taken by anyone who is allergic to it or has any other allergies. There may be inactive ingredients in this product that may cause allergic reactions. More information can be obtained from your pharmacist. Due to lower or higher blood sugar levels, you may experience blurred vision, dizziness, or drowsiness. It is not safe to drive, operate machinery, or perform any other activity that requires alertness or vision clarity until you are sure you can perform such activities safely. Drinking alcohol can increase your risk of low blood sugar when taking this medication. Sometimes alcohol interacts with glyburide and causes a serious reaction, which can cause symptoms like nausea, dizziness, or vomiting.

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