08045479576
08045479576
Ketorolac Tromethamine Powder
8000.0 INR/Kilograms
Product Details:
- EINECS No 255-968-1
- Molecular Formula C19H24N2O6
- HS Code 29339990
- Heavy Metal (%) Typical Heavy Metal Limits (as per USP, BP, EP standards): Total Heavy Metals (as Pb): 20 ppm (0.002%) Specific Heavy Metals: Lead (Pb): 0.5 ppm (0.00005%) Cadmium (Cd): 0.5 ppm (0.00005%) Arsenic (As): 1.5 ppm (0.00015%) Mercury (Hg): 0.5 ppm (0.00005%)
- Loss on Drying The Loss on Drying (LOD) for Ketorolac Tromethamine is typically 1.0% (as per USP and other pharmacopeial standards). Testing Method: Procedure: Determined by drying at 105 C under vacuum until a constant weight is achieved. Purpose: Ensures minimal moisture content to maintain stability, potency, and shelf life.
- Ph Level The pH level of Ketorolac Tromethamine depends on its formulation: Injectable Solution (IV/IM): pH 6.9 7.9 Ophthalmic Solution (Eye Drops, Acular): pH 7.4 (close to natural tear pH) Oral Solution (if dissolved): pH varies based on solvent but typically near neutral (7.0)
- Melting Point The melting point of Ketorolac Tromethamine is approximately 162-165 C (323-329 F).
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Ketorolac Tromethamine Powder Price And Quantity
- 25 Kilograms
- 8000.0 INR/Kilograms
Ketorolac Tromethamine Powder Product Specifications
- The Loss on Drying (LOD) for Ketorolac Tromethamine is typically 1.0% (as per USP and other pharmacopeial standards). Testing Method: Procedure: Determined by drying at 105 C under vacuum until a constant weight is achieved. Purpose: Ensures minimal moisture content to maintain stability, potency, and shelf life.
- Typical Heavy Metal Limits (as per USP, BP, EP standards): Total Heavy Metals (as Pb): 20 ppm (0.002%) Specific Heavy Metals: Lead (Pb): 0.5 ppm (0.00005%) Cadmium (Cd): 0.5 ppm (0.00005%) Arsenic (As): 1.5 ppm (0.00015%) Mercury (Hg): 0.5 ppm (0.00005%)
- The melting point of Ketorolac Tromethamine is approximately 162-165 C (323-329 F).
- 223.7 C
- The pH level of Ketorolac Tromethamine depends on its formulation: Injectable Solution (IV/IM): pH 6.9 7.9 Ophthalmic Solution (Eye Drops, Acular): pH 7.4 (close to natural tear pH) Oral Solution (if dissolved): pH varies based on solvent but typically near neutral (7.0)
- ( )-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Other
- Medicine Grade
- 29339990
- C19H24N2O6
- Typical Purity Standards: Pharmaceutical Grade: 98% (as per USP, BP, and EP standards) Analytical/Reagent Grade: 99% (for laboratory and research purposes) Raw API (Active Pharmaceutical Ingredient): Usually 98-99.5% purity
- White to Light yellow powder to crystal
- Ketorolac Tromethamine Usage 1. Pain Management: Used for short-term relief of moderate to severe pain (e.g., post-surgical pain, musculoskeletal pain). Typically prescribed for no more than 5 days due to potential side effects. 2. Postoperative Pain: Commonly used after surgeries (orthopedic, abdominal, dental, etc.) to reduce pain and inflammation. 3. Ophthalmic Use: Acular (Ketorolac eye drops) is used to reduce eye inflammation after cataract surgery and relieve seasonal allergic conjunctivitis. 4. Nasal Formulation (Sprix): Used for systemic pain relief via nasal absorption, often in patients who cannot take oral NSAIDs. Dosage Forms & Routes: Tablet (Oral) Typically 10 mg every 4-6 hours as needed. Injection (Intramuscular/Intravenous) Used in hospitals for severe pain. Ophthalmic Solution (Eye Drops) 0.5% solution for eye inflammation. Nasal Spray (Sprix) Alternative for those unable to take oral NSAIDs.
- Antipyretic Analgesics and NSAIDs
- 255-968-1
- 74103-07-4
- Toradol (ketorolac tromethamine)
- Bitter
- API (Active Pharmaceutical Ingredient) Particle Size: Micronized Form: 10 50 m (micrometers) Non-micronized Form: 50 200 m Injectable & Ophthalmic Formulations: Often undergoes finer milling to ensure proper solubility and bioavailability.
- 376.40 Grams (g)
- O || C6H5-C-CH2 \ N / \ O=C CH3 \ / C / \ CH2-CH2-COOH HOCH2C(CH2OH)3
- Solubility of Ketorolac Tromethamine Freely soluble in water Freely soluble in methanol Slightly soluble in ethanol Practically insoluble in non-polar solvents (e.g., hexane, chloroform) The tromethamine salt form improves its aqueous solubility, making it suitable for injectable and ophthalmic formulations.
- 3 Years
- Room Temperature
- No Smell
Ketorolac Tromethamine Powder Trade Information
- INDIA
- Cash Advance (CA) Cash in Advance (CID) Days after Acceptance (DA) Letter of Credit at Sight (Sight L/C) Letter of Credit (L/C)
- 100 Kilograms Per Day
- 7 Days
- Yes
- Free samples are available
- Drum/Bag Packing
- Asia Australia Central America North America South America Eastern Europe Western Europe Middle East Africa
- All India
- WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED
Product Description
Ketorolac Tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) used for short-term management of moderate to severe pain. It works by inhibiting prostaglandin synthesis, which helps reduce pain, inflammation, and fever.
Description:
- Drug Class: NSAID (Nonsteroidal Anti-inflammatory Drug)
- Formulations: Available in tablet, injection, and ophthalmic solution forms.
- Mechanism of Action: Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin production.
- Uses: Commonly prescribed for postoperative pain, musculoskeletal pain, and eye inflammation (ophthalmic use).
- Duration of Use: Typically limited to 5 days due to the risk of side effects.
Side Effects:
- Common: Nausea, dizziness, headache, gastrointestinal discomfort.
- Serious: Gastrointestinal bleeding, kidney damage, increased cardiovascular risks.
Contraindications:
- Not for chronic pain or minor aches.
- Avoid in patients with: Peptic ulcers, kidney disease, bleeding disorders, or those taking anticoagulants.
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