Ketorolac Tromethamine Powder

Name: Ketorolac Tromethamine Powder
Brand: SHREEJI PHARMA INTERNATIONAL
Price: 10500.0 INR
Availability: InStock

Price 10500.0 INR/ Kilograms

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MOQ : 25 Kilograms

Ketorolac Tromethamine Powder Specification

Boiling point
223.7 C

Molecular Weight
376.40 Grams (g)

Solubility
Solubility of Ketorolac Tromethamine Freely soluble in water Freely soluble in methanol Slightly soluble in ethanol Practically insoluble in non-polar solvents (e.g., hexane, chloroform) The tromethamine salt form improves its aqueous solubility, making it suitable for injectable and ophthalmic formulations.

Structural Formula
C6H5-C-CH2

Taste
Bitter

Particle Size
API (Active Pharmaceutical Ingredient) Particle Size: Micronized Form: 10 50 m (micrometers) Non-micronized Form: 50 200 m Injectable & Ophthalmic Formulations: Often undergoes finer milling to ensure proper solubility and bioavailability.

Storage
Room Temperature

Ph Level
The pH level of Ketorolac Tromethamine depends on its formulation: Injectable Solution (IV/IM): pH 6.9 7.9 Ophthalmic Solution (Eye Drops, Acular): pH 7.4 (close to natural tear pH) Oral Solution (if dissolved): pH varies based on solvent but typically near neutral (7.0)

Heavy Metal (%)
Typical Heavy Metal Limits (as per USP, BP, EP standards): Total Heavy Metals (as Pb): 20 ppm (0.002%) Specific Heavy Metals: Lead (Pb): 0.5 ppm (0.00005%) Cadmium (Cd): 0.5 ppm (0.00005%) Arsenic (As): 1.5 ppm (0.00015%) Mercury (Hg): 0.5 ppm (0.00005%)

Loss on Drying
The Loss on Drying (LOD) for Ketorolac Tromethamine is typically 1.0% (as per USP and other pharmacopeial standards). Testing Method: Procedure: Determined by drying at 105 C under vacuum until a constant weight is achieved. Purpose: Ensures minimal moisture content to maintain stability, potency, and shelf life.

HS Code
29339990

EINECS No
255-968-1

Shelf Life
3 Years

Molecular Formula
C19H24N2O6

Smell
No Smell

Melting Point
The melting point of Ketorolac Tromethamine is approximately 162-165 C (323-329 F).

Medicine Name
Toradol (ketorolac tromethamine)

Chemical Name
( )-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

CAS No
74103-07-4

Type
Antipyretic Analgesics and NSAIDs

Grade
Medicine Grade

Usage
Ketorolac Tromethamine Usage 1. Pain Management: Used for short-term relief of moderate to severe pain (e.g., post-surgical pain, musculoskeletal pain). Typically prescribed for no more than 5 days due to potential side effects. 2. Postoperative Pain: Commonly used after surgeries (orthopedic, abdominal, dental, etc.) to reduce pain and inflammation. 3. Ophthalmic Use: Acular (Ketorolac eye drops) is used to reduce eye inflammation after cataract surgery and relieve seasonal allergic conjunctivitis. 4. Nasal Formulation (Sprix): Used for systemic pain relief via nasal absorption, often in patients who cannot take oral NSAIDs. Dosage Forms & Routes: Tablet (Oral) Typically 10 mg every 4-6 hours as needed. Injection (Intramuscular/Intravenous) Used in hospitals for severe pain. Ophthalmic Solution (Eye Drops) 0.5% solution for eye inflammation. Nasal Spray (Sprix) Alternative for those unable to take oral NSAIDs.

Purity(%)
Typical Purity Standards: Pharmaceutical Grade: 98% (as per USP, BP, and EP standards) Analytical/Reagent Grade: 99% (for laboratory and research purposes) Raw API (Active Pharmaceutical Ingredient): Usually 98-99.5% purity

Appearance
White to Light yellow powder to crystal

Ketorolac Tromethamine Powder Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
mumbai

Payment Terms
Cash Advance (CA), Cash in Advance (CID), Days after Acceptance (DA), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)

Supply Ability
100 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
Drum/Bag Packing

Main Export Market(s)
Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa, Asia

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Ketorolac Tromethamine Powder

Ketorolac Tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) used for short-term management of moderate to severe pain. It works by inhibiting prostaglandin synthesis, which helps reduce pain, inflammation, and fever.

Description:

Drug Class: NSAID (Nonsteroidal Anti-inflammatory Drug)
Formulations: Available in tablet, injection, and ophthalmic solution forms.
Mechanism of Action: Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin production.
Uses: Commonly prescribed for postoperative pain, musculoskeletal pain, and eye inflammation (ophthalmic use).
Duration of Use: Typically limited to 5 days due to the risk of side effects.

Side Effects:

Common: Nausea, dizziness, headache, gastrointestinal discomfort.
Serious: Gastrointestinal bleeding, kidney damage, increased cardiovascular risks.

Contraindications:

Not for chronic pain or minor aches.
Avoid in patients with: Peptic ulcers, kidney disease, bleeding disorders, or those taking anticoagulants.

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