Levothyroxine Sodium

About Levothyroxine Sodium

We are offering high quality of Levothyroxine Sodium. We are known for manufacturing, exporting, Distributing, trading and supplying Levothyroxine Sodium in Gujarat, India. Further, this is safely Packaged by our professionals in diverse packaging options that maintain its purity and Effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Levothyroxine Sodium in Gujarat. India. Shreeji Pharma International manufacturing & supplying all products under GMP site with all types of regulatory supports. Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Levothyroxine Sodium Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Levothyroxine Sodium as well as Intermediates of Levothyroxine Sodium.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Levothyroxine Sodium to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries

Technical Specifications:

• Chemical Formula: CHINNaOxHO
• CAS Number: 25416-65-3
• Molecular Weight: Approximately 798.85 g/mol (anhydrous form)
• Synonyms: L-thyroxin sodium, levothyroxine sodium monohydrate
• Appearance: Light yellow to buff-colored, odorless, hygroscopic powder
•  Solubility: Slightly soluble in water; soluble in dilute sodium hydroxide solution
• Melting Point: 207210C (decomposes)
• Density: Approximately 2.381 g/cm
• Light Sensitivity: May assume a slight pink color upon exposure to light

Packaging & Storage

• Packaging: Tight, light-resistant containers
• Storage Conditions: Store at 28C; protect from light
• Stability: Stable in dry air; may discolor upon exposure to light

Introduction of product: Levothyroxine Sodium is the sodium salt of the synthetic levo-isomer of thyroxine (T), a major hormone secreted by the thyroid gland. It is used as a replacement therapy in patients with hypothyroidism, a condition where the thyroid gland fails to produce sufficient thyroid hormone. Levothyroxine acts by increasing the levels of thyroid hormone in the body, thereby restoring normal metabolic activity.

Levothyroxine Sodium Powder is typically used in the formulation of oral solid and liquid dosage forms and is also employed in veterinary applications. It is a potent, hygroscopic, and light-sensitive compound, requiring precise handling and formulation conditions. The powder is slightly soluble in water and demonstrates good solubility in dilute alkali solutions.

How does it work?: Levothyroxine Sodium is a synthetic form of thyroxine (T), one of the main hormones naturally produced by the thyroid gland. After administration, levothyroxine is absorbed into the bloodstream and undergoes conversion in peripheral tissues (primarily the liver and kidneys) to triiodothyronine (T), the biologically active thyroid hormone.

T binds to thyroid hormone receptors (TRs) located in the nucleus of cells throughout the body. Once bound, it modulates gene expression by interacting with thyroid response elements on DNA. This leads to:

• Increased basal metabolic rate (BMR)
• Enhanced oxygen consumption
• Improved protein synthesis
• Regulation of growth and development (especially crucial in infants and children)
• Proper functioning of the cardiovascular, nervous, and digestive systems

Applications. Or where it is used:

Sodium is primarily used as a thyroid hormone replacement therapy. Its applications span human medicine, veterinary medicine, and pharmaceutical manufacturing. Below are its main areas of use: