Polyethylene Glycol Manufacturer, Supplier, Exporter

Polyethylene Glycol PEG Specification

Shelf Life
3 Years

Solubility
Freely soluble in water - Soluble in ethanol, acetone - Insoluble in hydrocarbons

HS Code
29094900

Smell
No Smell

Molecular Weight
6000 Kilograms (kg)

Ph Level
~4.5 to 7.5 (5% aqueous solution depending on grade)

Loss on Drying
Typically <1.0% (as per pharmacopeial specs)

Boiling point
~250 C

Melting Point
~60 63 C

EINECS No
500-038-2

Heavy Metal (%)
0.001% (10 ppm or lower per pharmacopeial limits like USP/BP/EP)

Taste
Odorless

Particle Size
Typically < 200 mesh (for PEG 6000 etc.)

Storage
Dry Place

Structural Formula
HO CH CH O (CH CH O)_n H

Molecular Formula
H(OCH CH )_nOH

Medicine Name
Polyethylene Glycol (commonly referred to as PEG; PEG 3350 is a popular form in medicine)

Chemical Name
Polyethylene glycol (also called polyethylene oxide or polyoxyethylene depending on MW)

CAS No
25322-68-3

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
- Osmotic laxative (PEG 3350) - Drug delivery vehicle - Moisturizer in cosmetics - Solvent and stabilizer

Purity(%)
Typically 98% (Pharma or Industrial Grade)

Appearance
White powder, waxy solid, or clear viscous liquid (depends on MW)

Physical Form
Solid

Polyethylene Glycol PEG Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
Mumbai Port

Payment Terms
Cash Against Delivery (CAD), Cash on Delivery (COD), Cash Advance (CA), Cash in Advance (CID), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)

Supply Ability
100 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
Drum Packing

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Polyethylene Glycol PEG

Polyethylene glycol is a polyether compound with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide or polyoxyethylene, depending on its molecular weight. It is a laxative solution that increases the amount of water in the intestinal tract to stimulate bowel movements. It is used as a laxative to treat occasional constipation or irregular bowel movements. It may also be used for purposes not listed in this medication guide.

Polyethylene Glycol Properties:

Formula: C₂nH₄n+2On+1
Density: 1.12 g/cm
Soluble in: Water
Molar mass: 44.05n + 18.02 g/mol
IUPAC ID: poly(ethylene oxide), poly(oxyethylene)

How does it work

Constipation may be treated with polyethylene glycol 3350. This medication belongs to a group called osmotic laxatives. It works by retaining water in the stool. By increasing bowel movements and softening stool, it makes passing them much easier.

Applications Or where it is used

This polyether compound is polyethylene glycol (PEG) or macrogol. Pharmacies, cosmetics, and foods widely use it as an additive.

How to use

Add the powder to 4 to 8 ounces of water, juice, soda, coffee, or tea. Drink this mixture right away after stirring it. You should not save it for later. In 1 to 3 days after using the medication, polyethylene glycol 3350 is supposed to induce bowel movement.

Side effects

Possible side effects:

Nausea, vomiting, or severe stomach pain
Ulcerative colitis
Irritable bowel syndrome (IBS)
Kidney disease

Warnings and precautions while using this product

Pregnant women should not use it unless prescribed by a physician. Polyethylene Glycol 3350, NF may occasionally cause nausea, stomach fullness, cramps, diarrhea, and/or gas. Avoid taking if you are experiencing nausea, vomiting, abdominal pain, or distention, which may be caused by bowel obstructions.

Polyethylene Glycol (PEG) is a synthetic polyether compound that has a wide range of applications in pharmaceuticals, cosmetics, industry, and biotechnology. Here's a detailed overview:

Chemical Description

Chemical Name: Polyethylene glycol
Chemical Formula: H(OCHCH)OH
Molecular Structure: A repeating unit of ethylene glycol (CHCHO)
Molecular Weight (MW): Varies based on the number of repeating units (n). Common grades include PEG-200, PEG-400, PEG-600, PEG-3350, PEG-8000, etc.
- Low MW PEGs (PEG-200 to PEG-600) are liquids.
- High MW PEGs (PEG-1000 and above) are waxy solids.

Physical & Chemical Properties

Appearance: Colorless, odorless, viscous liquids or waxy solids depending on MW.
Solubility: Highly soluble in water, many organic solvents (alcohols, acetone), but insoluble in hydrocarbons.
Hygroscopic: Absorbs water from the air.
Non-volatile and chemically stable.
Biodegradability: PEGs are generally biodegradable, though the rate depends on MW and environmental conditions.

Uses and Applications

1. Pharmaceuticals

Laxatives: PEG-3350 is commonly used in over-the-counter and prescription laxatives (e.g., MiraLAX).
Drug Delivery: Used as a solvent, vehicle, or base in oral, topical, and injectable formulations.
PEGylation: The process of attaching PEG chains to drug molecules (e.g., proteins, enzymes) to improve:
- Solubility
- Stability
- Half-life
- Reduced immunogenicity

2. Cosmetics and Personal Care

Used in creams, lotions, toothpaste, deodorants, etc. as:
- Moisturizers (humectants)
- Emollients
- Solubilizers
- Surfactants

3. Industrial Uses

Lubricants and anti-foaming agents
Plasticizers in rubber and plastics
Binders in ceramics and other materials
Ink and paint formulations

4. Biotechnology and Research

Cell fusion and hybridoma technology
Protein precipitation in purification processes
Cryopreservation of cells and tissues

Safety and Toxicity

PEGs are generally regarded as non-toxic and non-irritating, although effects vary with MW.
Low MW PEGs can be absorbed through the skin or mucosa, while high MW PEGs are mostly inert.
In high doses (e.g., laxative use), may cause bloating, gas, diarrhea.
Hypersensitivity is rare but possible (e.g., anaphylaxis after PEGylated drugs or vaccines).

Environmental Impact

PEGs are water-soluble and usually biodegradable, but large-scale industrial use can raise concerns about aquatic toxicity depending on formulation and additives.