Tricalcium Citrate

Product Description

We are offering high quality of Tricalcium Citrate . We are known for manufacturing, exporting, distributing, trading and supplying Tricalcium Citrate   in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Tricalcium Citrate   in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Tricalcium Citrate . Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Tricalcium Citrate  as well as Intermediates of Tricalcium Citrate .  

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Tricalcium Citrate  to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Tricalcium Citrate is a calcium salt of citric acid, commonly used as a dietary supplement to provide calcium, an essential mineral for bone health and other physiological functions. It is a preferred form of calcium supplement because it is well-tolerated and highly bioavailable, meaning the body can absorb and use it efficiently.

Description & Properties:

Chemical Name: Tricalcium citrate

Chemical Formula: Ca(CHO)

Molecular Weight: 570.5 g/mol

Appearance: A white to off-white crystalline powder or granules.

Solubility: Slightly soluble in water but more soluble in acidic solutions, making it easier for the body to absorb when consumed with food or in a supplement form.

Odor: Odorless.

Uses and Applications:

Dietary Supplement: Tricalcium citrate is commonly used in calcium supplements, providing a source of calcium to prevent or treat calcium deficiencies, which may lead to conditions like osteoporosis or rickets.

Bone Health: It plays a vital role in maintaining bone density, strength, and overall skeletal health. Calcium is a crucial component of hydroxyapatite, the mineral matrix of bones.

Food and Beverage Fortification: Tricalcium citrate is added to fortified foods and beverages (such as juices, dairy substitutes, or cereals) to help ensure adequate calcium intake.

Antacid: It is sometimes used as a mild antacid to neutralize stomach acid, providing relief from conditions like heartburn or acid reflux.

Pharmaceutical Formulations: Tricalcium citrate is used in the preparation of pharmaceutical products, such as in the formulation of calcium supplements and certain types of oral medications.

Mechanism of Action:

When consumed, tricalcium citrate dissociates in the digestive system to release calcium ions (Ca), which are absorbed in the small intestine. These calcium ions play a key role in several vital functions in the body:

Bone Health: Calcium is essential for bone formation and maintenance. It helps regulate bone remodeling and ensures the bones remain strong and dense, which is important for preventing bone-related disorders like osteoporosis.

Muscle Contraction: Calcium ions are involved in the contraction of muscles. When calcium is released into the muscle cells, it interacts with proteins (like actin and myosin) to enable muscle contraction. It also aids in muscle relaxation.

Nerve Transmission: Calcium is important in the process of nerve signal transmission. It facilitates the release of neurotransmitters, which are essential for communication between nerve cells.

Blood Clotting: Calcium is involved in the coagulation cascade, a series of reactions that lead to the formation of a blood clot. Without calcium, blood would not clot properly.

Advantages of Tricalcium Citrate:

Better Absorption: Compared to other calcium salts (like calcium carbonate), tricalcium citrate is more easily absorbed by the body, particularly in individuals with lower stomach acid levels, which makes it ideal for older adults or people with conditions like gastritis or those taking acid-reducing medications.

Gentler on the Stomach: It is less likely to cause gastrointestinal discomfort, such as gas, bloating, or constipation, which can occur with other forms of calcium.

No Need for Food: Unlike calcium carbonate, which needs to be taken with food to aid absorption, tricalcium citrate can be taken with or without food.

Dosage and Administration:

The appropriate dosage of tricalcium citrate depends on the individuals age, dietary calcium needs, and specific health conditions. The typical recommended daily intake (RDI) of calcium for adults is about 1,0001,200 mg, but this may vary based on specific needs.

For calcium supplements, a typical dose of tricalcium citrate is around 500600 mg of calcium per serving, usually taken 1-3 times a day. The dose should be divided to optimize absorption and minimize side effects.

Side Effects:

While tricalcium citrate is generally safe, excessive intake of calcium can lead to several side effects, including:

Hypercalcemia: Elevated calcium levels in the blood, leading to symptoms like nausea, vomiting, constipation, fatigue, and confusion.

Kidney Stones: In some cases, excessive calcium intake can contribute to the formation of kidney stones, especially in individuals predisposed to stone formation.

Gastrointestinal Issues: Though gentler than calcium carbonate, some people may still experience bloating or gas with high doses of calcium.

Precautions:

Overdose: Taking too much calcium can lead to hypercalcemia or other health issues, so its important not to exceed the recommended dose without consulting a healthcare provider.

Interaction with Other Medications: Calcium can interact with certain medications, such as bisphosphonates, antibiotics, and thyroid medications. Its important to take calcium supplements at different times from these medications.

Kidney Disease: People with impaired kidney function should be cautious when taking calcium supplements, as they may have difficulty excreting excess calcium.

Heart Disease: Excess calcium can potentially affect the heart and blood vessels, so those with heart disease should consult their doctor before starting a calcium supplement regimen.

Storage:

Storage Conditions: Tricalcium citrate should be stored in a cool, dry place, away from moisture and heat. It should be kept tightly closed in its original container to protect it from environmental factors.

Shelf Life: Check the expiration date on the packaging and avoid using it beyond the recommended period.

Conclusion:

Tricalcium citrate is an effective and well-tolerated form of calcium supplementation. It is highly bioavailable, making it an excellent choice for people who need to increase their calcium intake, especially those with specific health concerns, such as osteoporosis, calcium deficiency, or digestive issues. As with any supplement, it should be used in accordance with recommended guidelines to avoid potential side effects or interactions.