
Clioquinol (also known as iodochlorhydroxyquinoline) is an antifungal and antibacterial agent, often used topically or in combination for treating skin infections and certain intestinal disorders.
Heres a summary of its key properties:
Chemical Name: 5-Chloro-7-iodo-8-quinolinol
Molecular Formula: C9H5ClINO
Molecular Weight: 305.5 g/mol
Appearance: Yellow to greenish-yellow crystalline powder
Solubility: Slightly soluble in water, more soluble in alcohol and chloroform
Melting Point: ~ 178182C
Odor: Odorless or very faint characteristic odor
Loss on Drying: Typically not more than 0.5% (per pharmacopeial standards, e.g., USP or Ph. Eur.)
Used in topical creams or ointments
Formerly used in oral formulations for protozoal and fungal infections, though its use is now restricted in many countries due to potential neurotoxicity (e.g., subacute myelo-optic neuropathy)
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