Clioquinol Api Powder

Clioquinol Api Powder About

Clioquinol (also known as iodochlorhydroxyquinoline) is an antifungal and antibacterial agent, often used topically or in combination for treating skin infections and certain intestinal disorders.

Heres a summary of its key properties:

Basic Information:

• Chemical Name: 5-Chloro-7-iodo-8-quinolinol

• Molecular Formula: C9H5ClINO

• Molecular Weight: 305.5 g/mol

• Appearance: Yellow to greenish-yellow crystalline powder

• Solubility: Slightly soluble in water, more soluble in alcohol and chloroform

Physicochemical Properties:

• Melting Point: 178182C

• Odor: Odorless or very faint characteristic odor

• Loss on Drying: Typically not more than 0.5% (per pharmacopeial standards, e.g., USP or Ph. Eur.)

Pharmaceutical Use:

• Used in topical creams or ointments

• Formerly used in oral formulations for protozoal and fungal infections, though its use is now restricted in many countries due to potential neurotoxicity (e.g., subacute myelo-optic neuropathy)