Diaminopyrimidine Oxide

About Diaminopyrimidine Oxide

Diaminopyrimidine Oxide is white to off-white crystalline powder that is used for increasing the volume of hair. It works by increasing the blood flow to the hair follicles through dilation of blood vessels. This compound is used in various hair cosmetics like shampoos, oil, conditioners, etc. to combat the loss of hair. It helps in the rejuvenation of hair roots so that growth of healthy hair can persist. This product reinforces hair anchoring as well as strengthens the hair from root to tip. It is easily absorbed by the skin. 

Molecular formula: C₄H₆N₄O

Molar mass: 126.12 g mol¹

Appearance: white odorless crystals

Melting point: 210218 C

Solubility in water: slightly soluble

Kopexil (INCI name diaminopyrimidine oxide, trade name Aminexil) is a chemical compound similar to minoxidil. Minoxidil was originally used to treat high blood pressure; a side effect was increased body hair. Both compounds have been used for therapy of alopecia.[2] Kopexil is not approved for use as a drug in the United States or in Europe.

Chemical structure

Kopexil is an N-oxide, a group of substances in which the nitrogen atom of a tertiary amine is oxidized. The compound can exist in two tautomeric forms.