Fluorescein Sodium

About Fluorescein Sodium

A sodium salt of fluorescein sodium is a fluorescent dye whose maximum emission wavelength is 512 nm, with peak excitation at 494 nm. For biomedical fluorescence imaging, visible wavelengths range from 400 nm to 700 nm, and the NIR spectrum extends from 700 nm to 900 nm.

A common method for evaluating the fit of RGP lenses uses sodium fluorescein (NaFl). Besides staining damaged epithelium, fluorescein should also be used to inspect the cornea and conjunctiva after rigid or soft lenses are removed.

How does it work :

To apply the paper strip to the eye, one should instill a small drop of sterile un-preserved saline on the fluorescein-coated tip and then gently touch the paper strip to the eye surface.

Applications Or where it is used:

An application of fluorescein sodium topically is routinely done in ophthalmology to measure tonometry and as a vital stain when a diagnosis of corneal ulcers, abrasions, or other epithelial defects is needed.

Manufacturing process:

Fluorescein is a synthetic coloring agent derived from an organic compound. Sodium phthalic anhydride and resorcinol are heated over a zinc catalyst, and they crystallize as deep red powder.

How to use:

Fluorescein is used to diagnose a variety of eye disorders. When applied directly to the eye or within a strip of paper, it helps detect eye injuries such as foreign bodies and corneal abrasions.

Dosage of usage:

Adult Dose- It is normal for adults to take 500 mg of FLUORESCITE Injection 10% (100 mg/mL) by intravenous administration.

Children should be given 7.7 mg for every kg of body weight (or 35 mg per 10 pounds of body weight) up to a maximum of 500 mg by intravenous administration.

Side effects :

• Difficulty breathing
• Difficulty swallowing
• Fast heartbeat
• Hives, itching, or skin rash
• Bluish color
• Cold, clammy skin
• Confusion
• Lightheadednes

Warnings and precautions while using this product

Fluorescein sodium can cause severe allergic reactions: Before any examination, a complete medical history must be taken, including any allergies, cardiopulmonary disease or concurrent treatments.