Febantel Api Powder

Product Description

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Febantel API Powder is the active pharmaceutical ingredient (API) used in the formulation of deworming medications. It is primarily used as an anthelmintic agent to treat parasitic worm infections in both humans and animals, such as dogs, cats, and livestock. Febantel is often used to treat infections caused by roundworms, hookworms, tapeworms, and whipworms.

Heres a detailed description of Febantel API Powder:

1. Active Ingredient

Febantel (chemical name: 2-(2,6-dimethylphenyl)-1,3-benzothiazol-3(2H)-one), is the active compound that is available in API powder form. It is a broad-spectrum anthelmintic agent, meaning it is effective against a wide variety of parasitic worm species.

3. Indications

Febantel is used to treat infections caused by gastrointestinal nematodes (roundworms, hookworms, whipworms) and some types of tapeworms. It is often used for:

Dogs and cats to treat intestinal worms.

Livestock: such as cattle, pigs, sheep, and goats to control parasitic infestations.

Some of the common parasitic infections treated with Febantel include:

Roundworms (e.g., Toxocara, Ascaris).

Hookworms (e.g., Ancylostoma).

Whipworms (e.g., Trichuris).

Tapeworms (e.g., Dipylidium).

4. Dosage and Administration

Febantel API powder is used as an active ingredient in various formulations (e.g., tablets, oral suspensions, or granules). The exact dosage and administration depend on the species and the type of infection being treated.

For animals, Febantel is usually administered orally, either directly or mixed with food.

Dosage recommendations often depend on body weight and the severity of the infection. For example:

Dogs and Cats: Common dosages range from 10 mg to 50 mg per kg of body weight, given as a single dose or multiple doses.

Livestock: Dosages depend on the species, with specific guidelines provided by veterinarians.

Note: The exact formulation and dosage should be determined by a veterinarian, particularly in case of young, pregnant, or sick animals.

5. Side Effects

Common side effects of Febantel include:

Vomiting or diarrhea in some animals after treatment.

Lethargy or mild digestive disturbances.

Rare side effects may include:

Allergic reactions or skin rashes.

Neurological effects (e.g., tremors or ataxia) in high doses.

6. Contraindications and Precautions

Pregnancy: Febantel should be used with caution during pregnancy. It is not typically recommended for use in pregnant animals unless the benefits outweigh the risks.

Young animals: Always ensure the correct dosage based on the age and weight of the animal.

Pre-existing conditions: Animals with liver or kidney diseases may need dose adjustments or avoidance of treatment.

7. Storage

Febantel API powder should be stored in a cool, dry place, away from moisture, heat, and direct sunlight.

The product should be kept in its original sealed packaging to prevent contamination.

Once the powder is incorporated into the final dosage form (e.g., tablet or suspension), the final product should be stored according to the manufacturers instructions, which often involve keeping it at room temperature or under cool conditions.

8. Chemical Structure

Febantel belongs to the benzothiazole family and contains a thiazole ring structure, which is common in anthelmintic drugs.

It has similar properties to fenbendazole, another well-known anthelmintic.

9. Packaging

Febantel API powder is typically supplied in bulk quantities, often in sealed drums or containers designed for use by pharmaceutical manufacturers. These containers are designed to protect the powder from contaminants and preserve its potency.

The powder is usually manufactured in pharmaceutical-grade forms for formulation into final products.