Glibenclamide in the offering is of high quality and highly demanded for its purity and effectiveness. It is safely packaged and supplied within India as well as outside India. Diabetes mellitus type two is treated with Glibenclamide, also called glyburide. Diet and exercise are recommended in conjunction with this supplement. It may be combined with other antidiabetic medications. It should not be used by itself for diabetes mellitus type 1. Your pancreas produces more insulin when you take glibenclamide. Sugar levels in your blood are reduced by this.
- CAS ID: 10238-21-8
- Formula: C23H28ClN3O5S
- Molar mass: 494.004 g/mol
- Synonyms: Glyburide
- melting point: 169 °C
- Boiling point :705.7±70.0 °C at 760 mmHg
- Purity: ≥ 99.0%
How does it work:
- Glibenclamide increases insulin production in the pancreas. Your blood sugar is reduced as a result.
- The drug acts by inhibiting the ATP-sensitive K+ channels, which results in insulin secretion and depolarization of cells. Additionally, the drug can have extrapancreatic effects on the liver, heart muscles, skeletal muscles, and smooth muscles.
Applications Or where it is used:
Type 2 diabetes mellitus is treated with glibenclamide. When combined with nutrition and exercise, this antidiabetic medication controls blood sugar levels in adults with type 2 diabetes. The pancreas releases more insulin to lower blood glucose levels.
How to use:
Your doctor usually recommends that you take this medication once a day with breakfast or with the first meal you eat that day. The patient may be advised to take this drug twice a day, especially those taking higher doses. Dosages are determined by your health conditions and treatment response. If you already take another diabetes medication, your doctor will tell you how to stop it and begin glyburide. Take glyburide four hours before colesevelam if you are also taking it.
Dosage of usage:
- Type 2 Diabetes Mellitus
- Regular tablets:
- Initial: 2.5-5 mg PO qDay
- Maintenance: 1.25-20 mg PO qDay or q12hr
- Do not exceed 20 mg/day
- Administer q12hr for doses >10 mg/day
- Transferring from insulin therapy to glyburide
- -Current insulin dose <20 units: Stop taking insulin and start glyburide dose at 2.5-5 mg/day (regular) or 1.5-3 mg/day (micronized)
- -Current insulin dose 20-40 units: Stop taking insulin and start glyburide dose at 5 mg/day (regular) or 3 mg/day (micronized)
Weight gain, nausea, heartburn, and stomach fullness are possible side effects. Tell your doctor or pharmacist if you experience any of these effects. Consult a doctor immediately if anyone experiences any serious side effects, such as easy bleeding/bruising, dark urine, stomach pain, yellowing eyes/skin, unusual tiredness, unusual weight gain, mood swings, seizures, etc.
Warnings and precautions while using this product:
Glyburide must not be taken by anyone who is allergic to it or has any other allergies. There may be inactive ingredients in this product that may cause allergic reactions. More information can be obtained from your pharmacist. Due to lower or higher blood sugar levels, you may experience blurred vision, dizziness, or drowsiness. It is not safe to drive, operate machinery, or perform any other activity that requires alertness or vision clarity until you are sure you can perform such activities safely. Drinking alcohol can increase your risk of low blood sugar when taking this medication. Sometimes alcohol interacts with glyburide and causes a serious reaction, which can cause symptoms like nausea, dizziness, or vomiting.