The sulfonylurea medication Glipizide is used to sensitize pancreatic beta cells and stimulate insulin release in people with Type 2 Diabetes. Lipizide is an oral hypoglycemic known as a second-generation sulfonylurea drug used to relieve symptoms of type 2 diabetes mellitus in patients with the disease.
Technical Specification :
- Molar Mass: 445.536 g/mol
- CAS NO: 29094-61-9
- DRUG CLASS: Sulfonylurea
- MELTING POINT: 208 to 209 °C (406 to 408 °F)
- FORMULA: C21H27N5O4S
How does it work:
Lipizide helps regulate insulin release after food consumption. A dose of glipizide can begin to have these effects in less than 30 minutes, even though peak plasma concentrations can take one to three hours. Lipizide is more effective if taken 30 minutes before eating.
Applications Or where it is used:
Lipizide is used to control blood sugar levels in people with type 2 diabetes, along with a proper diet and exercise program. It may also be combined with other diabetes medications. Diabetes prevents kidney damage, nerve problems, limb loss, blindness and problems with sexual function.
How to use:
The pills of Glipizide are available in both tablets and extended-release (long-acting) tablets for oral administration. It is usually taken before breakfast or a meal one or more times a day. An extended-release tablet is usually taken with breakfast once a day.
Dosage of usage:
Glipizide should be taken exactly as prescribed by your doctor. Follow your medication instructions carefully. Dosages may be changed occasionally by your doctor. The dose or duration of taking this medicine shouldn't be altered.
- You should take the regular tablet 30 minutes before the first meal of the day.
- Taking glipizide extended-release with your first meal of the day is appropriate.
- Avoid crushing, chewing, or breaking the tablet and swallow it whole.
Side effects :
- Muscle tremors
Warnings and precautions while using this medicine:
- Glipizide should not be taken by people with diabetic ketoacidosis
- Before taking this medicine
- The medication shouldn't be used if you are allergic to glipizide or if you have diabetic ketoacidosis (talk to your doctor).
Tell your doctor if you have ever had:
- Liver or kidney disease
- Chronic diarrhea or a blockage in intestines
- An enzyme deficiency known as glucose-6-phosphate dehydrogenase deficiency (G6PD)
When you are pregnant, or when you become pregnant, take glipizide as directed by your doctor. High blood sugar during pregnancy is dangerous for the mother as well as the baby, and it can cause complications. During your last 2 weeks of pregnancy, you should avoid taking glipizide. Women with diabetes who are pregnant are currently advised to use other agents besides glipizide to treat the condition.