Hydroxyzine HCL

Product Description

We are offering high quality of Hydroxyzine HCL. We are known for manufacturing, exporting, distributing, trading and supplying Hydroxyzine HCL in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Hydroxyzine HCL in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier of Hydroxyzine HCL. Nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Hydroxyzine HCL as well as Intermediates of Hydroxyzine HCL.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Hydroxyzine HCL to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Hydroxyzine HCL is a first-generation antihistamine with a range of uses, including treatment of anxiety, nausea, allergies, and insomnia, as well as serving as a sedative. Here are the technical details:

Chemical Information:

IUPAC Name: 2-[2-(4-chlorophenyl)ethoxy]ethanamine hydrochloride

Molecular Formula: C21H27ClN2HCl

Molecular Weight: 374.87 g/mol

CAS Number: 58-35-9

Synonyms: Atarax, Vistaril, Anxan, Meprospan

2. Common Uses

Anxiety Relief: Often prescribed to manage anxiety or tension, especially for short-term use.

Allergy Symptoms: Hydroxyzine can treat allergy symptoms like hives, itching, or rashes.

Nausea and Vomiting: It is used to treat nausea or vomiting, including post-surgery.

Sleep Disorders: Hydroxyzine can be used short-term to help with sleep issues, particularly if related to anxiety or stress.

Preoperative Sedation: It is used as a sedative before surgery to calm patients.

3. Mechanism of Action

Histamine Blockade: Hydroxyzine works by blocking the effects of histamine, a chemical involved in allergic reactions and the regulation of sleep-wake cycles.

CNS Depression: It has a central nervous system depressant effect, which accounts for its sedative and calming properties.

4. Dosage Forms

Tablets: Available in oral tablet form for ease of use.

Syrup: Available as an oral syrup for easier administration, especially for children.

Injectable: Hydroxyzine can be given by injection in hospital settings for more immediate effects.

5. Side Effects

Common side effects may include:

Drowsiness or sedation (common and expected)

Dry mouth

Dizziness

Blurred vision

Constipation

Headache

Serious side effects (less common but requiring medical attention):

Rapid or irregular heartbeats

Allergic reactions (rash, itching, swelling)

Difficulty breathing

6. Precautions and Warnings

Avoid Alcohol: Hydroxyzine may increase the sedative effects of alcohol, leading to severe drowsiness and impaired coordination.

Pregnancy and Breastfeeding: Use cautiously during pregnancy, especially in the first trimester. It is excreted in breast milk, so it should be avoided during breastfeeding unless prescribed by a healthcare provider.

7. Interactions

Hydroxyzine can interact with other medications, including:

CNS Depressants: Medications like alcohol, sedatives, and tranquilizers can increase sedation and drowsiness when used with hydroxyzine.

Anticholinergic Drugs: Concurrent use with other medications that have anticholinergic effects (e.g., certain antidepressants, antihistamines) may increase side effects like dry mouth or blurred vision.

8. Brand Names and Availability

Hydroxyzine is available under various brand names, including:

Vistaril

Atarax These brands may offer different formulations, but they all contain the same active ingredient, hydroxyzine hydrochloride.

Hydroxyzine is often prescribed as a short-term solution for anxiety or other issues, due to its potential for drowsiness and dependence on regular use. Always follow the prescribed dosage and consult a healthcare provider for any concerns regarding side effects or drug interactions.