Itraconazole Chemical

The antifungal medication itraconazole, often abbreviated as ITZ, is used to treat a variety of fungal infections. In this category are aspergillosis, histoplasmosis, blastomycosis, coccidioidomycosis, and paracoccidioidomycosis. You can take it orally or intravenously. It is an antifungal medication used to treat fungal infections in adults. Any infection in the body, whether it's the lungs, mouth, throat, or toenails or fingernails. Depending on the brand, itraconazole may not be appropriate for treating nail fungal infections.

Technical Specifications:

• CAS ID: 84625-61-6
• Synonyms : Sporanox, Sporanox Pulsepak
• Molecular Formula: C35H38Cl2N8O4
• Molecular Weight: 705.6
• Melting point: 170°C
• Boiling point: 850 °C
• Solubility: Freely soluble in methylene chloride, insoluble in water, very slightly soluble in ethanol

How does it work:

Itraconazole oral solution (liquid) is used to treat yeast infections affecting the mouth, throat, or esophagus (tube connecting the throat and stomach). This antifungal belongs to a group of drugs known as triazoles. Triazoles act by slowing the growth of infection-causing fungi.

Applications Or where it is used:

Toenail fungal infections can be treated with itraconazole tablets and capsules. Infections of the mouth and throat, as well as of the esophagus (tube that connects the throat to the stomach), can be treated with itraconazole oral solution (liquid). The most important treatment option for dermatophyte infections of glabrous skin is itraconazole, which is used together with fluconazole, terbinafine, ketoconazole, and griseofulvin. 

How to use:

Itraconazole oral solution is typically taken once or twice a day on an empty stomach for 1 to 4 weeks. If there is any part of the prescription label that you do not understand, ask your doctor or pharmacist. Follow the directions on the prescription label exactly. Avoid opening, chewing, or crushing itraconazole capsules. You will probably not see any improvement in your nails until they grow new ones if you are taking itraconazole to treat a nail infection.

Dosage of usage:

You should take itraconazole capsules with food. Sporanox PulsePak is prescribed under a special schedule that does not involve taking the medicine daily for several days. Always follow the directions on the label. Itraconazole is typically taken for at least three months in order to treat fungal infections in the lungs. The capsules are usually taken one or two times a day during or right after a full meal. For serious fungal infections of the lungs, itraconazole capsules should be taken every three hours with a meal for the first three days of treatment, then once or twice a day with a meal for at least three months.

Side effects:

For signs of an allergic reaction, please seek emergency medical attention: hives, tingling in your arms or legs, rash, breathing difficulties, swelling in your face, lips, tongue, or throat. 

Do not stop taking itraconazole, but contact your physician as soon as you experience any of the following symptoms:

•  Confusion
• Blurred or double vision
• Ringing in your ears
• Fast or irregular heartbeats
• Numbness or tingly feeling
•  Loss of bladder control
• Leg cramps
• Constipation
• Increased thirst or urination
• Muscle weakness 
• Nausea and vomiting
• Liver problems

Warnings and precautions while using this product:

If you've had heart failure in the past, you shouldn't take itraconazole. If you suffer from liver or kidney disease, you should avoid taking itraconazole along with colchicine, fesoterodine, or solifenacin. The drug can harm a developing fetus. You should not become pregnant while taking itraconazole and for 2 months after you finish taking it. The combination of itraconazole with certain other medications can have life-threatening side effects.