Methylprednisolone Aceponate

215000 INR/Kilograms

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Product Details:

Melting Point Between 135° to 139°
Storage Room Temperature
Solubility soluble in chloroform, ethyl acetate
Molecular Weight 472.57 Grams (g)
Molecular Formula C27H36O7
Loss on Drying NMT 1.0%w/w
Chemical Name Methylprednisolone Aceponate
Supply Ability : 1000 Kilograms Per Month
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Price And Quantity

Price Range 215000.00 - 220000.00 INR/Kilograms
Price 215000 INR/Kilograms
Minimum Order Quantity 25 Kilograms

Product Specifications

Loss on Drying NMT 1.0%w/w
Type Pharmaceutical Intermediates
Chemical Name Methylprednisolone Aceponate
Molecular Formula C27H36O7
Solubility soluble in chloroform, ethyl acetate
Appearance White crysatlline powder
Molecular Weight 472.57 Grams (g)
Grade Cosmetic Grade
Usage Methylprednisolone aceponate (MPA) has been shown to provide rapid, reliable and highly effective treatment of eczematous disorders, with an efficacy comparable to that of most reference topical corticosteroids. It also has excellent local and systemic tolerability.
Physical Form Powder
Storage Room Temperature
CAS No 86401-95-8
Melting Point Between 135° to 139°

Trade Information

FOB Port Any indian port
Payment Terms Letter of Credit (L/C), Cash in Advance (CID), Cash Advance (CA), Cash on Delivery (COD), Cash Against Delivery (CAD)
Supply Ability 1000 Kilograms Per Month
Delivery Time 1 Week
Sample Policy Free samples are available
Packaging Details drum packing
Main Domestic Market All India
Certifications ISO GMP

Product Description

Methylprednisolone aceponate, also known as methylprednisolone acetate propionate is available under the brands Advantan and Avancort in the market. It is a glucocorticoid and a corticosteroid ester— particularly the C21 acetate diester and C17α propionate of methylprednisolone.

Properties:

Description: white crystalline powder
Solubility: soluble in chloroform, Ethyl acetate
Identification: The infrared spectrum of the sample is concordant to that of the standard
Melting Point: 135.4
Loss on drying : 0.56%
Assay: 99.1%
Particle size: complies

How does it work?

There is strong evidence that MPA has the ability to quickly, reliably and highly effectively treat eczematous disorders, with effectiveness equivalent to most reference topical steroids. It also has excellent local and systemic tolerability.

Manufacturing process:

The present invention is related to a procedure for synthesising methyl prednisolone aceponate. As an initial material for its synthesis, methyl prednisolone is used, followed by reaction with propionic acid, cyclic ester hydrolysis with 200-300 mesh G-type silica gel as a catalyst, and finally reaction with acetic acid. This invention produces methyl prednisolone aceponate products that are of high purity, have a low rate of side products, and are simple, mild in reaction conditions, and can easily be used in industrial production.

Side effects:

Skin thinning
Appearance of fine blood vessels on the skin surface
Stretch marks
Acne
Infection of hair follicles
Excessive unwanted hair growth
Redness and irritation around the mouth (perioral dermatitis)
Skin discolouration

Warnings and precautions while using this product

Do not use methylprednisolone if you are allergic to it, prednisone, or if you have any other allergies. It is possible that this product contains inactive ingredients that are harmful to health. If you wish to know more, contact your pharmacist.