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Methylprednisolone Aceponate

Methylprednisolone Aceponate

215000 INR/Kilograms

Product Details:

  • Melting Point Between 135 to 139
  • Molecular Weight 472.57 Grams (g)
  • Loss on Drying NMT 1.0%w/w
  • Molecular Formula C27H36O7
  • Storage Room Temperature
  • Solubility soluble in chloroform, ethyl acetate
  • Chemical Name Methylprednisolone Aceponate
  • Supply Ability : 1000 Kilograms Per Month
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Price And Quantity

  • 25 Kilograms
  • 215000 INR/Kilograms
  • 215000.00 - 220000.00 INR/Kilograms

Product Specifications

  • Pharmaceutical Intermediates
  • soluble in chloroform, ethyl acetate
  • 86401-95-8
  • NMT 1.0%w/w
  • C27H36O7
  • Room Temperature
  • Powder
  • Cosmetic Grade
  • 472.57 Grams (g)
  • Methylprednisolone Aceponate
  • Between 135 to 139
  • White crysatlline powder
  • Methylprednisolone aceponate (MPA) has been shown to provide rapid, reliable and highly effective treatment of eczematous disorders, with an efficacy comparable to that of most reference topical corticosteroids. It also has excellent local and systemic tolerability.

Trade Information

  • Any indian port
  • Letter of Credit (L/C), Cash in Advance (CID), Cash Advance (CA), Cash on Delivery (COD), Cash Against Delivery (CAD)
  • 1000 Kilograms Per Month
  • 1 Week
  • Free samples are available
  • drum packing
  • All India
  • ISO GMP

Product Description

Methylprednisolone aceponate, also known as methylprednisolone acetate propionate is available under the brands Advantan and Avancort in the market. It is a glucocorticoid and a corticosteroid ester particularly the C21 acetate diester and C17 propionate of methylprednisolone.

Properties:

  • Description: white crystalline powder
  • Solubility: soluble in chloroform, Ethyl acetate
  • Identification: The infrared spectrum of the sample is concordant to that of the standard
  • Melting Point: 135.4
  • Loss on drying : 0.56%
  • Assay: 99.1%
  • Particle size: complies

How does it work?


There is strong evidence that MPA has the ability to quickly, reliably and highly effectively treat eczematous disorders, with effectiveness equivalent to most reference topical steroids. It also has excellent local and systemic tolerability.

Manufacturing process:


The present invention is related to a procedure for synthesising methyl prednisolone aceponate. As an initial material for its synthesis, methyl prednisolone is used, followed by reaction with propionic acid, cyclic ester hydrolysis with 200-300 mesh G-type silica gel as a catalyst, and finally reaction with acetic acid. This invention produces methyl prednisolone aceponate products that are of high purity, have a low rate of side products, and are simple, mild in reaction conditions, and can easily be used in industrial production.

Side effects:

  • Skin thinning
  • Appearance of fine blood vessels on the skin surface
  • Stretch marks
  • Acne
  • Infection of hair follicles
  • Excessive unwanted hair growth
  • Redness and irritation around the mouth (perioral dermatitis)
  • Skin discolouration

Warnings and precautions while using this product


Do not use methylprednisolone if you are allergic to it, prednisone, or if you have any other allergies. It is possible that this product contains inactive ingredients that are harmful to health. If you wish to know more, contact your pharmacist.
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