Methylprednisolone Aceponate

Price 215000.0 INR/ Kilograms

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MOQ : 25 Kilograms

Methylprednisolone Aceponate Specification

Smell
No Smell

Ph Level
5.0 and 7.0.

Melting Point
Between 135 to 139

Shelf Life
3 Years

HS Code
3004.90

Taste
Bitter

Molecular Weight
472.57 Grams (g)

EINECS No
264-422-9

Solubility
slightly soluble in water

Heavy Metal (%)
< 10 ppm

Storage
Room Temperature

Loss on Drying
1.0%

Molecular Formula
C27H36O7

Chemical Name
Methylprednisolone Aceponate

CAS No
86401-95-8

Type
Pharmaceutical Intermediates

Grade
Cosmetic Grade

Usage
Methylprednisolone aceponate (MPA) has been shown to provide rapid, reliable and highly effective treatment of eczematous disorders, with an efficacy comparable to that of most reference topical corticosteroids. It also has excellent local and systemic tolerability.

Purity(%)
98% or 99%

Appearance
White crysatlline powder

Physical Form
Powder

Methylprednisolone Aceponate Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
mumbai

Payment Terms
Cash Against Delivery (CAD), Cash on Delivery (COD), Cash Advance (CA), Cash in Advance (CID), Letter of Credit (L/C)

Supply Ability
1000 Kilograms Per Month

Delivery Time
1 Week

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
drum or bag packing

Main Export Market(s)
Australia, North America, South America, Western Europe, Middle East

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Methylprednisolone Aceponate

Methylprednisolone aceponate, also known as methylprednisolone acetate propionate is available under the brands Advantan and Avancort in the market. It is a glucocorticoid and a corticosteroid ester particularly the C21 acetate diester and C17 propionate of methylprednisolone.

Properties:

Description: white crystalline powder
Solubility: soluble in chloroform, Ethyl acetate
Identification: The infrared spectrum of the sample is concordant to that of the standard
Melting Point: 135.4
Loss on drying : 0.56%
Assay: 99.1%
Particle size: complies

How does it work?

There is strong evidence that MPA has the ability to quickly, reliably and highly effectively treat eczematous disorders, with effectiveness equivalent to most reference topical steroids. It also has excellent local and systemic tolerability.

Manufacturing process:

The present invention is related to a procedure for synthesising methyl prednisolone aceponate. As an initial material for its synthesis, methyl prednisolone is used, followed by reaction with propionic acid, cyclic ester hydrolysis with 200-300 mesh G-type silica gel as a catalyst, and finally reaction with acetic acid. This invention produces methyl prednisolone aceponate products that are of high purity, have a low rate of side products, and are simple, mild in reaction conditions, and can easily be used in industrial production.

Side effects:

Skin thinning
Appearance of fine blood vessels on the skin surface
Stretch marks
Acne
Infection of hair follicles
Excessive unwanted hair growth
Redness and irritation around the mouth (perioral dermatitis)
Skin discolouration

Warnings and precautions while using this product

Do not use methylprednisolone if you are allergic to it, prednisone, or if you have any other allergies. It is possible that this product contains inactive ingredients that are harmful to health. If you wish to know more, contact your pharmacist.

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