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Ondansetron Api Powder

Price 8500.0 INR/ Kilograms

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MOQ : 25 Kilograms, Kilograms

Ondansetron Api Powder Specification

EINECS No
620-535-6

Solubility
Slightly soluble in water, soluble in methanol and ethanol

Molecular Weight
293.37 Kilograms (kg)

Boiling point
Not applicable (decomposes on heating)

Taste
Bitter

Molecular Formula
C18H19N3O

Loss on Drying
Usually: 0.5% w/w (weight/weight) moisture content

Storage
Room Temperature

Heavy Metal (%)
10 ppm (parts per million)

Particle Size
Usually micronized or sieved for uniform particle size distribution

Structural Formula
O || / \ | | | __ | | / \___| | \__/ \ \_______/\ | \ CH2-N CH3 | Imidazole ring | CH3

Melting Point
Approximately 181-184 C

Ph Level
pH around 3.5 to 5.5 depending on concentration and formulation.

Smell
No Smell

HS Code
30049099

Shelf Life
5 Years

Medicine Name
Ondansetron Hydrochloride

Chemical Name
9-Methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one

CAS No
99614-02-5

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
Ondansetron is primarily used as an antiemetic a drug that prevents or treats nausea and vomiting. It is especially effective when these symptoms are caused by chemotherapy, radiation therapy, or surgery.

Purity(%)
98%

Appearance
White to off-white crystalline powder

Physical Form
Powder

Ondansetron Api Powder Trade Information

Minimum Order Quantity
25 Kilograms, Kilograms

FOB Port
Mumbai Port

Payment Terms
Cash Against Delivery (CAD), Cash Advance (CA), Cash in Advance (CID), Delivery Point (DP), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)

Supply Ability
100 Kilograms, Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
Drum Packing

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Ondansetron Api Powder

We have been able to attain strong market goodwill as a trusted organization engaged in offering Ondansetron Hydrochloride. It is used as a semi-synthetic macrolide antibiotic. This drug prevents bacteria from growing, by interfering with their protein synthesis. It binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Ondansetron Hydrochloride has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly legionella pneumophila. It can treat respiratory tract, urinary and soft tissue infections.

Ondansetron API Powder: Detailed Description

Chemical Name: Ondansetron
Chemical Formula: C18H19N3O
Molecular Weight: 293.37 g/mol
CAS Number: 99614-02-5

What is Ondansetron?

Ondansetron is a selective 5-HT3 receptor antagonist used primarily as an antiemetic to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It works by blocking serotonin, a natural substance that may cause nausea and vomiting, from binding to 5-HT3 receptors in the brain and gastrointestinal tract.

Physical Characteristics of Ondansetron API Powder

Appearance: White to off-white crystalline powder
Solubility: Slightly soluble in water, soluble in methanol and ethanol
Melting Point: Approximately 181-184C
Particle Size: Usually micronized or sieved for uniform particle size distribution
Odor: Odorless or faintly characteristic

Pharmacological Profile

Mechanism of Action: Ondansetron selectively antagonizes serotonin 5-HT3 receptors located both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the brain, thereby preventing the vomiting reflex.
Bioavailability: High oral bioavailability (about 60%)
Half-life: Approximately 3-4 hours in healthy adults

Manufacturing and Quality Control

Purity: High purity (>99%) is required for pharmaceutical use
Identification Tests: UV spectroscopy, HPLC, and IR spectroscopy to confirm identity and purity
Impurities: Strict control on residual solvents, heavy metals, and other impurities per pharmacopeial standards (e.g., USP, EP)
Stability: Stable under recommended storage conditions (cool, dry, away from light)

Applications of Ondansetron API Powder

Pharmaceutical Formulations: Tablets, oral solutions, injectable formulations
Indications: Prevention and treatment of nausea and vomiting associated with cancer chemotherapy, radiation therapy, and postoperative conditions

Storage Conditions

Store in a cool, dry place away from moisture and direct sunlight.
Typically stored in tightly closed containers to prevent contamination and degradation.