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Phenylbutazone (BP, EP, USP)
Phenylbutazone (BP, EP, USP) Phenylbutazone (BP, EP, USP) Phenylbutazone (BP, EP, USP) Phenylbutazone (BP, EP, USP) Phenylbutazone (BP, EP, USP)

Phenylbutazone (BP, EP, USP)

1100.0 INR/Kilograms

Product Details:

  • Shelf Life 3 Years
  • Melting Point 97 C 103 C
  • Smell No Smell
  • Taste Bitter
  • Loss on Drying 0.5%
  • Storage Dry Place
  • Molecular Weight 312.37 Kilograms (kg)
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Phenylbutazone (BP, EP, USP) Price And Quantity

  • 25 Kilograms
  • 1100.0 INR/Kilograms
  • 25.00 - 50.00 INR/Kilograms

Phenylbutazone (BP, EP, USP) Product Specifications

  • 98.0% (USP/BP/EP grade)
  • 29332100
  • Solid
  • C19H20N2O2
  • White or almost white crystalline powder
  • 200-029-1
  • Commonly micronized, 90% < 100 m (can vary)
  • 0.001% (10 ppm max, per pharmacopeial limits)
  • Decomposes before boiling
  • Non-steroidal anti-inflammatory drug (NSAID); used in veterinary and limited human applications
  • O || Ph N N Ph | | C C4H9 || O
  • Slightly acidic to neutral in aqueous suspension (not highly soluble in water)
  • Slightly soluble in water, soluble in alcohol, chloroform, and ether
  • 50-33-9
  • Medicine Grade
  • 312.37 Kilograms (kg)
  • 0.5%
  • Phenylbutazone
  • Dry Place
  • Pharmaceutical Intermediates
  • No Smell
  • Bitter
  • 97 C 103 C
  • 3 Years
  • 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione

Phenylbutazone (BP, EP, USP) Trade Information

  • Mumbai Port
  • Cash Advance (CA) Cash in Advance (CID) Days after Acceptance (DA) Letter of Credit at Sight (Sight L/C) Cash on Delivery (COD) Letter of Credit (L/C)
  • 100 Kilograms Per Day
  • 7 Days
  • Yes
  • Free samples are available
  • Drum Packing
  • Asia Australia North America Africa Central America South America Eastern Europe Western Europe Middle East
  • All India
  • WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

Product Description

Phenylbutazone (BP, EP, USP) Detailed Description

We are creating a brand name in every part of the national market by offering our clients Phenylbutazone. This drug has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It is also useful in rheumatoid arthritis and reiter's syndrome. This drug comes in the firm of injection, tablet or oral suspension. Phenylbutazone is odorless white or off-white crystalline powder with bitter taste. Clients can avail our drug in different quantity packaging options and at reasonable prices from us.

1. Chemical Identity

  • Chemical Name: 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione

  • Chemical Formula: C19H20N2O2

  • Molecular Weight: 312.37 g/mol

  • Structure: It is a pyrazolidinedione derivative with two phenyl groups and a butyl side chain.


2. Physical Description

  • Appearance: White or almost white crystalline powder or crystals.

  • Solubility: Slightly soluble in water, soluble in alcohol, chloroform, and ether.


3. Pharmacopoeial Standards

a. British Pharmacopoeia (BP)

  • Identification Tests: IR spectrum, UV spectrum, and specific chemical reactions confirm identity.

  • Assay: Typically uses titration or chromatographic methods (HPLC) to determine purity and content. Should contain not less than 98.0% and not more than 102.0% of C19H20N2O2.

  • Related Substances: Limits on impurities and degradation products defined. Uses chromatography (e.g., HPLC) for quantification.

  • Loss on Drying: Usually less than 0.5%, ensuring minimal moisture content.

  • Residue on Ignition: Usually less than 0.1%.

  • Heavy Metals: Controlled to a defined low limit.

  • Microbial Limits: Specified to ensure product safety.

b. European Pharmacopoeia (EP)

  • Similar to BP in identification methods and purity requirements.

  • Assay: May specify HPLC method with defined mobile phase, column type, and detection wavelength.

  • Impurities: Lists specific known impurities with maximum allowable limits.

  • Physical Properties: Melting point usually ranges from 97 C to 103 C.

  • Other Tests: Tests for heavy metals, residual solvents, and microbial contamination.

c. United States Pharmacopeia (USP)

  • Identification: IR spectrum, UV absorbance, and chromatographic profile.

  • Assay: Typically by HPLC or titration. Assay range usually between 98.0% and 102.0%.

  • Impurities: Limits on known impurities and degradation products.

  • Physical Properties: White crystalline powder, melting point around 97-103 C.

  • Microbial Limits: USP sets limits for non-sterile products.


4. Pharmacological Properties

  • Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

  • It works by inhibiting cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.


5. Storage and Handling

  • Store in a well-closed container, protected from light and moisture.

  • Stable under normal conditions but sensitive to prolonged exposure to air and light.


6. Usage

  • Historically used to treat inflammatory conditions such as arthritis and gout.

  • Due to side effects, its use in humans has declined but it is still used in veterinary medicine.

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