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Pioglitazone API Powder

Price 1200.0 INR/ Kilograms

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MOQ : 25 Kilograms

Pioglitazone API Powder Specification

Shelf Life
5 Years

Smell
No Smell

Boiling point
190.0 to 197.0 C.

Melting Point
182 186 C

Particle Size
Typically D90 < 10 microns (varies by specification)

Heavy Metal (%)
10 ppm

Ph Level
around 4.4 mg/mL at pH 1.2

Storage
Room Temperature

Loss on Drying
0.5%

Molecular Weight
356.44 Kilograms (kg)

Solubility
Practically insoluble in water; soluble in DMSO, DMF, methanol, ethanol

EINECS No
220-908-2

Taste
Bitter

HS Code
29349900

Molecular Formula
C19H20N2O3S

Medicine Name
Pioglitazone

Chemical Name
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

CAS No
111025-46-8

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
Treatment of Type 2 Diabetes Mellitus (Antidiabetic)

Purity(%)
99% (Pharmaceutical Grade)

Appearance
White to off-white crystalline powder

Physical Form
Powder

Pioglitazone API Powder Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
Mumbai Port

Payment Terms
Cash Advance (CA), Cash in Advance (CID), Days after Acceptance (DA), Delivery Point (DP), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)

Supply Ability
100 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
Drum Packing

Main Export Market(s)
North America, Asia, Australia, Central America, Middle East, South America, Eastern Europe, Western Europe, Africa

Main Domestic Market
All India

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Pioglitazone API Powder

Powder Pioglitazone For Pharma is a high-grade pharmaceutical powder that meets BP and Technical Grade standards. It is a fine powder that is commonly used in the pharmaceutical industry to treat type 2 diabetes. The product comes in a white powder form and is typically stored at room temperature. It is used to lower blood sugar levels and improve insulin sensitivity in patients with type 2 diabetes. This powder is also used in industrial settings for various applications. Its versatility and purity make it a popular choice among manufacturers and suppliers. This product is ideal for distributors, exporters, manufacturers, suppliers, and traders in the pharmaceutical and industrial sectors.

Pioglitazone API powder is the pure, active pharmaceutical ingredient used in medications to treat type 2 diabetes. It belongs to the thiazolidinedione class and works by improving insulin sensitivity, reducing insulin resistance, and ultimately lowering blood sugar levels.

Detailed Description:

Mechanism of Action:

Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-), a nuclear receptor that plays a role in regulating glucose and lipid metabolism. This activation leads to increased insulin sensitivity in muscle, adipose tissue, and the liver, reducing insulin resistance and improving glucose disposal.

Formulation:

It's used in the formulation of oral antidiabetic medications, often as a component of tablets or other oral dosage forms.

Manufacturing:

Pioglitazone API powder is manufactured under strict quality standards to ensure purity, stability, and consistency.

Uses:

It's primarily used to treat type 2 diabetes mellitus in adults as an adjunct to diet and exercise, and sometimes in combination with other antidiabetic medications.

Safety:

Pioglitazone has been associated with some safety concerns, including fluid retention and an increased risk of heart failure in some individuals. Therefore, its use should be carefully considered in patients with heart failure or at risk of developing it.