Pyrantel Pamoate

Product Description

Pyrantel Pamoate of high quality is an effective treatment for infections caused by worms in the intestiles, like roundworm, pinworm, and hookworm. It is an anthelmintic medication. Paralyzing the worms allows the body to naturally remove them in the stool.

Technical Specifications:

• Product Name: Pyrantel Pamoate
• Synonyms:  4,4 -Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid compound with 1,4,5,6-Tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyrimidine; Antiminth; 1,4,5,6-Tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyrimidine
• CAS Number: 22204-24-6
• Molecular Formula: C₁₁H₁₄N₂SC₂₃H₁₆O₆
• Molecular Weight: 594.68
• Boiling Point: 642.7^o C
• Melting Point: 266-267^o C 
• Description: Yellow to tan solid
• Solubility: Insoluble in water and in Methanol, slightly soluble in Dimethyl Formamide and soluble in Dimethyl sulfoxide
• Loss on drying (Under vacuum at 60C for 3hrs): Not more than 2.0 % w/w
• Residue on ignition: Not more than 0.5%
• Heavy metals: Not more than 50 ppm
• Iron: Maximum 0.0075%
• Pamoic acid Content by HPLC (On dried basis): 63.4% to 67.3%
• Assay by HPLC (On dried basis): 97.0 % to 103.0 %

How does it work?

Pyrantel is classified as an anthelmintic, which makes the parasites immobile (paralyzed), allowing the body to rid itself of them naturally. Pinworm infections may be self-treated using Pyrantel.

Applications Or where it is used:

Pinworm, roundworm, and hookworm are among the intestinal worm infections treated by this prescription drug. The drug Pyrantel is an anthelmintic.

How to use:

If your doctor has prescribed it, you can take it with or without food. As directed by your doctor, take this medication by mouth once per day. You may take it with milk or fruit juice. A laxative is not necessary with this medication.

Dosage of usage:

Before using the over-the-counter product, read all instructions on the package. You can also find the Patient Information Leaflet with the medicine and read it attentively. You should understand how to identify pinworms, what pinworm infections look like, and how to avoid getting infected again. For more information, please consult your doctor or pharmacist. Be sure to shake well before using this medication. Follow the direction of your doctor to take this medication with or without food.

Side effects:

Following are the side effects which may occur. Tell your doctor or pharmacist right away if any of these effects persist or worsen.

• Vomiting
• Nausea
• Diarrhea
• Stomach/abdominal cramps
• Headache
• Drowsiness
• Dizziness
• Trouble sleeping
• Loss of appetite

Warnings and precautions while using this product

Before taking pyrantel, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of:  liver disease, severe lack of nutrition (malnutrition).

Pyrantel Pamoate - Drug Description

Generic Name: Pyrantel Pamoate
Drug Class: Anthelmintic (Anti-parasitic)
Formulations: Available as oral suspension, chewable tablets, and capsules
Mechanism of Action: Pyrantel pamoate is a depolarizing neuromuscular blocker that paralyzes susceptible worms by interfering with their nervous system. The paralyzed worms lose their grip on the intestinal wall and are expelled from the body through natural bowel movements.

Indications & Uses:

Pyrantel pamoate is used to treat:

• Pinworm infections (Enterobius vermicularis)
• Roundworm infections (Ascaris lumbricoides)
• Hookworm infections (Necator americanus, Ancylostoma duodenale)
• Other susceptible intestinal worm infections

Dosage & Administration:

• Typical Dosage: Administered as a single oral dose based on body weight (usually 11 mg/kg).
• Repeat Dosing: May be necessary for reinfection or persistent cases.

Side Effects:

• Mild gastrointestinal symptoms (nausea, vomiting, diarrhea, abdominal cramps)
• Dizziness, headache, or fatigue
• Rare allergic reactions

Precautions & Warnings:

• Not recommended for individuals with liver disease without medical supervision.
• Use in pregnant and breastfeeding women should be discussed with a doctor.
• Proper hygiene (handwashing, washing clothes/bedding) is crucial to prevent reinfection.