Simethicone 30% Emulsion
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1. Overview
Simethicone is an anti-foaming agent used to relieve bloating, discomfort, and pain caused by excessive gas in the stomach and intestines. It works by breaking up gas bubbles, making it easier for the body to expel them.
Simethicone 30% emulsion is a liquid formulation containing 30% Simethicone, typically used in pharmaceutical and industrial applications.
CompositionActive Ingredient: Simethicone (30%)
Excipients: Purified water
Emulsifiers (e.g., polysorbate 80) Preservatives (if applicable)
Mechanism of Action Simethicone acts as a surface-active agent, reducing surface tension in gas bubbles within the digestive tract. This action prevents bubble formation and allows gas to be expelled more easily through burping or flatulence.
Used in antiflatulent medications for treating gas, bloating, and discomfort.
Helps in conditions like functional dyspepsia, gastroesophageal reflux disease (GERD), and irritable bowel syndrome (IBS).
Often included in antacid formulations.
Used in endoscopic procedures to reduce gas formation.
Employed in the food and beverage industry to control foam in certain liquid formulations.
Used in cosmetic and personal care products as a defoaming agent.
Oral use (for pharmaceuticals): Usually diluted or incorporated into formulations like suspensions, drops, or chewable tablets.
Typical Dosage: Varies depending on the formulation but is commonly 20-125 mg per dose, taken after meals or at bedtime.
Dosage should be as directed by a healthcare provider.
Side Effects Generally well-tolerated with minimal side effects.
Rarely, mild effects such as: Nausea Diarrhea Allergic reactions (rash, itching)
Precautions & Warnings
Safe for most individuals, including pregnant and breastfeeding women (consult a doctor).
Not absorbed into the bloodstream, making it safe for long-term use.
Avoid if allergic to simethicone or its excipients.
Storage Conditions Store at room temperature (15-30C).
Keep in a tightly closed container, away from moisture and light.
Shake well before use (if in liquid suspension form).
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