Sodium starch glycolate is the sodium salt of carboxymethyl ether. Starch glycolates are of rice, potato, wheat or corn origin. Sodium starch glycoate is a white to off-white, tasteless, odorless, relatively free flowing powder.
Sodium starch glycolate is used as a pharmaceutical grade dissolution excipient for tablets and capsules. It absorbs water rapidly, resulting in swelling which leads to rapid disintegration of tablets and granules. It is used as a disintegrant, a suspending agent and as a gelling agent. Without a disintegrant, tablets may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.
Sodium Starch Glycolate Properties:
- Synonyms: Sodium carboxymethyl starch
- CAS No.: 9063-38-1
- Solubility: This substance is practically insoluble in organic solvents and water, very hygroscopic, and produces a translucent suspension in water.
- pH: Between 5.5 to 7.5
- Iron: Sample solution color is a pink shade no darker than that of standard solution (0.002%).
- Sodium Chloride: NMT 7.0%
- Sodium glycolate: NMT 2.0%
- Loss on drying (at 130°C for 90 min) NMT: 10.0%
- Assay: Between 2.8% to 4.2 %
How does it work
The stable and disintegrating properties of sodium starch glycolate make it a useful chemical. Black particles are not present in this white material. A maize and potato starch is used to prepare it.
Applications Or where it is used
This is used as a disintegrant, a suspending agent, and a gelling agent.
How to use
Water can immediately dissolve Sodium Starch Glycolate, releasing the medicine at the point of contact. It is suitable for direct compression or wet granulation
There are no side effects associated with sodium starch glycolate. Nevertheless, it can cause adverse effects in certain individuals depending on where it comes from. Those with corn allergies or celiac disease may suffer adverse effects.
Warnings and precautions while using this product
Eyes, skin, and respiratory tracts may be affected. There is no information on the target organ. If ingested, it may cause digestive irritation. Possible respiratory tract irritation with inhalation.