Trihexyphenidyl Hydrochloride is highly pure and effective product manufactured to GMP standards at the facility located in Gujarat. It along with its intermediates are exported to many countries worldwide.
- CAS Number: 52-49-3
- Name: 1-Piperidinepropanol, a-cyclohexyl-a-phenyl-, hydrochloride (1:1)
- Superlist Name: Benzhexol hydrochloride
- Formula: C20H32ClNO
- Molecular Weight: 337.93
- Deleted CAS: 58947-95-8
- Synonyms: 1-Piperidinepropanol,a-cyclohexyl-a-phenyl-, hydrochloride (6CI,7CI,8CI,9CI);1-Phenyl-1-cyclohexyl-3-piperidyl-1-propanol hydrochloride; Paralest; Pargitan; Parkinol; Parkisan; Partigan; Sedrina; Trihexy; Trihexyphenidyl chlorhydrate;Tsiklodol;a-Cyclohexyl-a-phenyl-1-piperidinepropanolhydrochloride;
- EINECS: 200-142-5
- Boiling Point: 447.9 °C at 760 mmHg
- Flash Point: 211 °C
- Solubility: soluble in water
- Risk Codes: 22
- Safety: 36
Introduction of product:
Trihexyphenidyl is an antispasmodic drug which can be used as an adjunct drug to manage parkinsonism and treat extrapyramidal symptoms because of drugs that affect the central nervous system (CNS).
How does it work:
- Trihexyphenidyl is classified as an anticholinergic drug. It is a group of medications that work in a similar manner. Often, these drugs are used in the treatment of similar conditions.
- Trihexyphenidyl blocks the functions of the part of your nervous system that controls your movements of body. As a result, certain muscles are relaxed and moving freely is easier.
Applications. Or where it is used :
Along with other medications, trihexyphenidyl is used to treat Parkinson's disease symptoms and to control extrapyramidal side effects caused by certain drugs.
How to use:
Trihexyphenidyl is used for treating Parkinson's disease symptoms or involuntary movements associated with certain psychiatric medications. This medication is in the class of medications known as anticholinergics, which block a specific natural substance (acetylcholine). Parkinson's patients using this product experience decreased muscle stiffness, sweating, and salivation, as well as improved walking skills. A class of medications known as anticholinergics can relieve severe muscle spasms of the back, neck, and eyes that are sometimes brought about by psychiatric drugs. Additionally, it can decrease the likelihood of muscle stiffness and rigidity (extrapyramidal signs-EPS). Movement problems caused by tardive dyskinesia may be further aggravated by the treatment.
Dosage of usage:
- Adult dosage (ages 18–59 years)
- Typical starting dosage: 1 mg per day as a single dose.
- Dosage increases: As soon as your symptoms do not subside, your doctor may increase your doses and wait until they do.
- Typical maintenance dosage: A daily dose can be between 5mg and 15mg. The dosage depends on how well your symptoms are controlled.
Note: It may be possible to improve your symptoms if your dosage of the medication causing them is reduced while you use trihexyphenidyl.
- Drowsiness may occur from the oral tablet trihexyphenidyl. Additional side effects can also occur.
More common side effects :
These are some of the more common side effects of trihexyphenidyl use:
Additionally, children using this drug have reported the following side effects:
- Dry mouth
- Blurred vision
- Trouble urinating
- Trouble sleeping
- Weight loss
- Muscle spasms
- Involuntary body movements
It may take a few days or a few weeks for mild side effects to disappear. if they're severe or don't go away, speak to your pharmacist or doctor.
Serious side effects
You should contact your doctor if you experience any serious side effects. There can be serious side effects and their symptoms, including:
Glaucoma. Symptoms can include:
- Irregular heartbeats
Intestinal problems. Symptoms can include:
- Tunnel vision
- Rainbow-colored circles around bright lights
- Eye pain
- Blurred vision
- Sudden or gradual loss of vision
Heat stroke or trouble sweating or both. Symptoms can include:
- Loss of appetite
- Severe constipation
- Stomach pain
Neuroleptic malignant syndrome (NMS). Symptoms include:
- Inability to sweat
- Muscle or stomach cramps
- Fast pulse
- Fast and shallow breathing
- High or low BP
- Rigid muscles
- Involuntary movements
- Mental status changes
Warnings and precautions while using this product:
Heat stroke warning: The risk of heat stroke increases when taking trihexyphenidyl. It reduces sweating, which results in the body being less able to keep cool. Hyperthermia (very high body temperature) becomes more likely. Heat stroke occurs when your body gets too hot and cannot cool down.
- Neuroleptic malignant syndrome warning: Trihexyphenidyl, a rare but life-threatening condition, can develop if you suddenly stop or reduce your dosage too quickly. During treatment with this drug, contact your doctor if you notice any of the following symptoms: high fever, muscle stiffness, slowed thoughts, rapid heartbeat, or sweating.
- Dementia warning: An anticholinergic medication, as determined by research from Trusted Source, increases your risk of developing dementia.