Benfotiamine .

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MOQ : 25 Kilograms

Benfotiamine . Specification

Solubility
Benfotiamine is a lipid-soluble derivative of thiamine (vitamin B1) with low solubility in water.

HS Code
29362290

Storage
Room Temperature

Loss on Drying
not more than 1.5%

Melting Point
>165 C

Boiling point
745.1 C

Shelf Life
3 Years

Smell
No Smell

Molecular Weight
466.4 Grams (g)

Molecular Formula
C19H23N4O6PS

Taste
Odorless

Medicine Name
Benfotiamine

Chemical Name
S-benzoylthiamine O-monophosphate

CAS No
22457-89-2

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
Benfotiamine is a vitamin supplement used to treat and prevent Vitamin B1 deficiency, including conditions like alcoholism-related nerve damage, and diabetic neuropathy. It's also effective in managing mental health symptoms and preventing Beriberi disease.

Purity(%)
98%

Appearance
Benfotiamine is a solid, typically a white powder or solid form.

Physical Form
Powder

Benfotiamine . Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
MUMBAI

Payment Terms
Cash Advance (CA), Cash in Advance (CID)

Supply Ability
1000 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
DRUM & BAG PACKING

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED.

About Benfotiamine .

Benfotiamine in the offering Benfotiamine, that is dephosphorylated to S-benzoylthiamine by ecto-alkaline phosphatases found in the intestinal mucosa. It is then hydrolyzed by thioesterase in the liver into thiamine. Transketolase activity is promoted by benfotiamine on peripheral tissues.

Technical Specifications:

Superlist Name: Benfotiamine
CAS No.: 22457-89-2
Formula: C19H23N4O6PS
Molecular Weight: 466.45
Synonyms: Milgamma;Neurostop;Nitanevril;S-BenzoylthiamineO-monophosphate;Tabiomyl;Vitanevril;Benzenecarbothioicacid, S-[2-(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl]ester (9CI);Formamide,N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-,S-benzoate O-(dihydrogen phosphate) (8CI);8088CB;BTMP;Benzoylthiamine O-monophosphate;Berdi;Betivina;Biotamin;
EINECS: 245-013-4
Density: 1.444 g/cm3
Melting Point: 165 Degree C
Boiling Point: 745.1 Degree C at 760 mmHg
Flash Point: 404.4 Degree C
Solubility: Soluble in water
Appearance: White crystalline powder
Molar mass: 466.45 gmol

How does it work?

A mechanism by which Benfotiamine works is by modulating the advanced glycation end products (AGEs). However, it can also act via non-AGE-dependent mechanisms. Advanced glycation end products are modified proteins or lipids that are formed into non-enzymatically glycated when exposed to sugars like aldose.

Applications Or where it is used:

A lot of people use benfotiamine for diabetic neuropathy (diabetic nerve damage). It is used for a variety of conditions such as alcohol use disorder, Alzheimer disease, arthritis, and others, but research supports few of them.

Manufacturing process:

The production of benfotiamine involves certain steps: taking polyphosphoric acid as the esterification reagent, reacting with vitamin B1, carrying out hydrolysis at extreme temperature post the end of reaction, and extracting phosphoric acid using trioctylamine.

How to use:

In 3-6 weeks, 150-600 mg Benfotiamine has been reported to provide relief from nerve pain associated with diabetes (diabetic neuropathy). A specific combination of benfotiamine and vitamin B12 providing 50 mg and 250 mcg, respectively, has been taken three times daily for three weeks.

Dosage of usage:

Adults usually take 150-600 mg of Benfotiamine daily by mouth for up to six months. If you have a particular condition, you should speak with your healthcare provider about the ideal dose.

Side effects:

Taking Benfotiamine by mouth for up to 24 weeks at a dose of 600 mg per day may be safe. The most common side effects are stomach distress and skin rash.
Warnings and precautions while using this product:
Pregnancy and breast-feeding: Benfotiamine isn't safe to use if you're pregnant or nursing. It's best to keep away from it.