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Benfotiamine .

Benfotiamine .

25.00 - 50.00 INR

Product Details:

  • Molecular Weight ‎466.4 Grams (g)
  • Storage Room Temperature
  • Molecular Formula CHNOPS
  • Medicine Name Benfotiamine
  • Type Pharmaceutical Intermediates
  • Grade Medicine Grade
  • Purity(%) 98%
  • Supply Ability : 1000 Kilograms Per Day
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Price And Quantity

  • 25 Kilograms
  • 25.00 - 50.00 INR

Product Specifications

  • CHNOPS
  • 98%
  • Medicine Grade
  • Pharmaceutical Intermediates
  • Benfotiamine
  • ‎466.4 Grams (g)
  • Room Temperature

Trade Information

  • Cash in Advance (CID), Cash Advance (CA)
  • 1000 Kilograms Per Day
  • 7 Days
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia

Product Description

Benfotiamine in the offering Benfotiamine, that is dephosphorylated to S-benzoylthiamine by ecto-alkaline phosphatases found in the intestinal mucosa. It is then hydrolyzed by thioesterase in the liver into thiamine. Transketolase activity is promoted by benfotiamine on peripheral tissues.

Technical Specifications: 

 

  • Superlist Name: Benfotiamine
  • CAS No.: 22457-89-2
  • Formula: C19H23N4O6PS
  • Molecular Weight: 466.45
  • Synonyms: Milgamma;Neurostop;Nitanevril;S-BenzoylthiamineO-monophosphate;Tabiomyl;Vitanevril;Benzenecarbothioicacid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl]ester (9CI);Formamide,N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-,S-benzoate O-(dihydrogen phosphate) (8CI);8088CB;BTMP;Benzoylthiamine O-monophosphate;Berdi;Betivina;Biotamin;
  • EINECS: 245-013-4
  • Density: 1.444 g/cm3
  • Melting Point: 165 oC
  • Boiling Point: 745.1 oC at 760 mmHg
  • Flash Point: 404.4 oC
  • Solubility: Soluble in water
  • Appearance: White crystalline powder
  • Molar mass: 466.45 g·mol−1

 

 


How does it work?

 

 

A mechanism by which Benfotiamine works is by modulating the advanced glycation end products (AGEs). However, it can also act via non-AGE-dependent mechanisms. Advanced glycation end products are modified proteins or lipids that are formed into non-enzymatically glycated when exposed to sugars like aldose.

Applications Or where it is used:

 

 

A lot of people use benfotiamine for diabetic neuropathy (diabetic nerve damage). It is used for a variety of conditions such as alcohol use disorder, Alzheimer disease, arthritis, and others, but research supports few of them.

Manufacturing process:

 

 

The production of benfotiamine involves certain steps: taking polyphosphoric acid as the esterification reagent, reacting with vitamin B1, carrying out hydrolysis at extreme temperature post the end of reaction, and extracting phosphoric acid using trioctylamine. 

How to use: 

 

 

In 3-6 weeks, 150-600 mg Benfotiamine has been reported to provide relief from nerve pain associated with diabetes (diabetic neuropathy). A specific combination of benfotiamine and vitamin B12 providing 50 mg and 250 mcg, respectively, has been taken three times daily for three weeks.

Dosage of usage: 

 

 

Adults usually take 150-600 mg of Benfotiamine daily by mouth for up to six months. If you have a particular condition, you should speak with your healthcare provider about the ideal dose.

Side effects:

 

 

  • Taking Benfotiamine by mouth for up to 24 weeks at a dose of 600 mg per day may be safe. The most common side effects are stomach distress and skin rash.
  • Warnings and precautions while using this product:
  • Pregnancy and breast-feeding: Benfotiamine isn't safe to use if you're pregnant or nursing. It's best to keep away from it.

 


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