Soluble in acetone, in alcohol, in carbon disulfide, in chloroform, and in ether; freely soluble in methylene chloride.
C10H20N2S4
C10H20N2S4 or ((C2H5)2NCS)2S2disulfiram
1-3 Years
White to off-white crystalline powder.
Room Temperature
117 C
Odorless
98%
156.2 - 161.6 F (69 - 72 C) / 160.7 F (71.5 C)
Disulfiram is used to treat chronic alcoholism. It causes unpleasant effects when even small amounts of alcohol are consumed. These effects include flushing of the face, headache, nausea, vomiting, chest pain, weakness, blurred vision, mental confusion, sweating, choking, breathing difficulty, and anxiety.
Backed with know-how and comprehension in this domain, we are engaged in offering Disulfiram powder. It is carbamate derivative used as an alcohol deterrent. This compound is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. The compound is used in oral drug for treating alcoholism. Alcohol is converted in the body into acetaldehyde by an enzyme called alcohol dehydrogenase. It prevents acetaldehyde dehydrogenase from converting acetaldehyde into acetic acid, leading to a buildup of acetaldehyde levels in the blood.
How does it work?
Disulfiram blocks the breakdown of alcohol in the body. As a result, a toxic alcohol-related compound builds up in the body, which can seriously harm people who drink alcohol while taking this medication. As a result, people are encouraged to avoid alcohol while taking the medication.
Applications Or where it is used
The drug disulfiram is used to treat chronic alcoholism. Alcohol causes unpleasant effects when it is consumed even in small amounts. There may be flushing of the face, weakness, blurry vision, mental confusion, sweating, choking, headaches, nausea, vomiting, chest pain, breathing difficulties, and anxiety.
Manufacturing process
In order to formulate Disulfiram Tablets, wet granulation will be used. A solution of binder will be prepared by using water. To ensure smooth blend flow and free of any defects in tableting, the formulation will be optimized regarding composition and process.
Dosage of usage
Usual Adult Dose for Alcohol Dependence:
Initial dose: 500 mg orally once a day continuously for 1 to 2 weeks
Maintenance dose: 250 mg orally once a day (range: 125 mg to 500 mg once a day)
Maximum dose: 500 mg once a day
Duration of therapy
Therapy may last months or even years
Side effects
Disulfiram may cause serious side effects including: