The third-generation antihistamine levocetirizine, marketed as Xyzal, is used for the treatment of allergic rhinitis and hives of unknown cause. Compared to older antihistamines, it is less sedating. The drug works by blocking an allergic reaction-triggering chemical (histamine). There is no evidence to suggest levocetirizine prevents or treats hives, anaphylaxis, or other severe allergies.
- CAS ID: 130018-77-8
- Molecular Formula: C21H27Cl3N2O3
- Molecular weight : 461.8
- Boiling point: 542.1 C
- Melting Point: 214 C
- Synonyms : (R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy]
- Solubility: Freely soluble in water
Levocetirizine belongs to the class of medications called antihistamines. As a result, it blocks the effect of histamine, which is the cause of allergic symptoms. As an antihistamine, levocetirizine is used to treat symptoms such as watery eyes, runny noses, itchy eyes and noses, and sneezing due to allergies. Additionally, it is used to relieve itching and hives.
Applications Or where it is used:
During an allergic reaction, your body makes a substance called histamine which is blocked by the drug. Levocetirizine does not prevent or treat hives or severe allergic reactions (such as anaphylaxis). Keep your epinephrine injector handy if you have been prescribed it to treat allergic reactions. Use epinephrine instead of levocetirizine.
You should take this medication by mouth once a day in the evening, with or without food. You must measure the dose carefully if you are using the liquid form of this medication. A household spoon may not deliver the correct dose.
Dosage of usage:
- You should take the medication according to your age, the condition you are treating, how severe the condition is, and how you react to the first dose. An adult typically takes one 5-mg tablet once every evening.
- Special dosage considerations: Mild kidney disease: 2.5 mg once per day.
- Moderate kidney disease: 2.5 mg once every other day.
- Severe kidney disease: 2.5 mg twice per week (taken once every 34 days).
You may feel drowsy, tired, and have a dry mouth. It is also possible to have a fever, especially in children. Your doctor or pharmacist should be notified right away if any of these side effects persist or worsen. An allergic reaction is very rare with this medication. Get medical help if any of the following symptoms occur: rash, itchy/swelling, difficulty breathing and severe dizziness.
Warnings and precautions while using this product:
Levocetirizine should not be used by people allergic to it or to cetirizine (Zyrtec). Dialysis patients or those with end-stage kidney disease should not take levocetirizine. Levocetirizine is not recommended for children younger than 12 years old with kidney disease. Breast-feeding is not recommended while you are using this medication. Children younger than 6 months old should not use levocetirizine.