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Guaifenesin is a medication primarily used as an expectorant to help relieve chest congestion. Here's a breakdown of its technical details:
Chemical Information:
IUPAC Name: 3-(2-methoxyphenoxy)-1,2-propanediol
Molecular Formula: C10H14O4
Molar Mass: 198.22 g/mol
CAS Number: 93-14-1
Uses:
Chest Congestion: Its commonly used to relieve symptoms of chest congestion caused by respiratory infections.
Cough: Guaifenesin is often combined with other medications (such as dextromethorphan or antihistamines) in products meant to treat cough and cold.
Bronchitis and other respiratory conditions: It is beneficial in reducing the discomfort associated with these conditions.
Forms Available: Guaifenesin is available in various forms, including:
Oral tablets and capsules
Syrups
Extended-release formulations
Granules and powder for reconstitution in liquid form
Dosage: The dosage of guaifenesin depends on the specific product and the age of the person taking it. Typically, it is taken every 4 to 6 hours, but you should always follow the instructions on the package or as prescribed by a healthcare provider.
Adults and children 12 years and older: 200 to 400 mg every 4 hours.
Children 6 to 12 years: 100 to 200 mg every 4 hours.
Children 2 to 6 years: 50 to 100 mg every 4 hours.
Side Effects: Guaifenesin is generally well-tolerated, but some people may experience side effects, including:
Nausea
Vomiting
Dizziness
Headache
Rash
Stomach upset Although rare, more severe allergic reactions could occur, leading to symptoms such as swelling, difficulty breathing, or hives. If any of these symptoms appear, seek immediate medical attention.
Precautions and Warnings:
Pregnancy and Breastfeeding: Guaifenesin is considered safe to use during pregnancy, but always consult with a healthcare provider before using it. It is excreted in breast milk, so caution is advised if breastfeeding.
Kidney or Liver Problems: People with kidney or liver conditions should consult their doctor before using guaifenesin, as their body may process the drug differently.
Other Medications: It is important to check with a healthcare provider before using guaifenesin, especially if you are taking other medications, as drug interactions are possible.
Combination Products: Guaifenesin is often included in combination products with other medications for treating colds, such as decongestants (like pseudoephedrine), antihistamines (like diphenhydramine), or cough suppressants (like dextromethorphan). Be cautious when taking combination products to avoid exceeding the recommended dose of any active ingredient.
Effectiveness: Guaifenesin's effectiveness in relieving chest congestion can vary. Some studies suggest that it may only modestly improve symptoms compared to a placebo, though many people find relief from their symptoms with its use. If symptoms persist, its advisable to consult a healthcare provider.
Conclusion:
Guaifenesin is a widely-used and generally safe expectorant to relieve chest congestion. While it can help loosen mucus and ease the symptoms of respiratory conditions, its always a good idea to follow dosing guidelines and consult with a healthcare provider if there are concerns or underlying health issues.
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