Triclabendazole Api Powder

Product Description

We are offering high quality of Triclabendazole . We are known for manufacturing, exporting, distributing, trading and supplying Triclabendazole in in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier Triclabendazole in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

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Shreeji Pharma International currently export Triclabendazole to countries like Gulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Triclabendazole is an antiparasitic medication used primarily to treat infections caused by liver flukes, particularly Fasciola hepatica and Fasciola gigantica. These parasitic flatworms can cause fascioliasis, a disease that affects the liver in humans and animals.

Here are key details about Triclabendazole:

1. Mechanism of Action

Triclabendazole works by inhibiting the metabolism of the liver fluke, disrupting its ability to produce energy. It specifically interferes with the flukes' microtubule function, preventing them from maintaining their structural integrity, which leads to the death of the parasites.

2. Indications

Fascioliasis: Triclabendazole is most commonly used to treat infections with Fasciola hepatica and Fasciola gigantica.

Other Uses: It may also be used for other parasitic infections caused by trematodes (flukes), though its primary use remains liver fluke infections.

3. Dosage and Administration

Triclabendazole is usually administered as a single dose or in divided doses depending on the severity of the infection.

It is commonly taken orally in tablet form.

Dosage can vary based on age, weight, and the type of infection, but a typical regimen for adult patients might be 10 mg/kg of body weight.

4. Side Effects

Common side effects of Triclabendazole may include:

Nausea

Abdominal pain

Diarrhea

Headache

Dizziness In rare cases, it may cause more serious side effects, like liver dysfunction, though these are not common.

5. Contraindications

Triclabendazole should not be used in people with:

Known hypersensitivity or allergic reactions to the drug.

Severe liver dysfunction (unless under strict medical supervision).

6. Pharmacokinetics

Absorption: Triclabendazole is absorbed from the gastrointestinal tract after oral administration, but its bioavailability is relatively low.

Metabolism: It is metabolized in the liver into its active form, which is responsible for its therapeutic effects.

Excretion: The drug and its metabolites are excreted primarily through feces.

7. Drug Interactions

There are no major known drug interactions, but caution should be used if the patient is taking other medications that affect liver function or other antiparasitic drugs.

8. Safety and Effectiveness

Triclabendazole is considered highly effective for treating liver fluke infections, often leading to significant improvement in symptoms.

It is generally well-tolerated, but, as with any medication, its use should be monitored by a healthcare professional.

9. Availability

Triclabendazole is available under various brand names, and its availability may vary by country. In some regions, it is marketed under the brand names Fasinex and Egaten.

If you need specific dosing details or have concerns about its use, its always a good idea to consult with a healthcare provider.