Piroctone olamine is the ethanolamine salt of the hydroxamic acidderivative piroctone. It is often used inÂ anti-dandruff shampooÂ asa replacement for the commonly used compound zinc pyrithione.
CAS Number:Â 68890-66-4
Kopirox (Piroctone Olamine)
Piroctone Olamine is known for its bacteriostatic and fungistaticproperties specifically working against Pityrosporumovale, which lives on theskin and is associated with dandruff and other manifestations of flaking on theface and scalp. It is often used in shampoo as a replacement of commonly usedZinc Pyrithione. It has been used over 30 years in the personal careformulations and also used as preservative and thickening agent.
Brand Name : Kopirox
INCI Name : Piroctone Olamine
Chemical Name :1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)pyridinone,2-aminoethanolsalt
CAS No : 68890-66-4
Molecular weight : 298.42
EI NECS : 272-574-2
Appearance : Powder form
1. Hair shedding and hair thinning have been reported to be affected bydandruff and seborrheic dermatitis.
2. In a comparative clinical study, it was demonstrated that PiroctoneOlamine outperformed Ketoconazole and Zinc Pyrithione based shampoo in its abilityto increase hair shaft diameter inn androgenic alopecia.
3. Piroctone Olamine also reduced sebum production.
4. Piroctone Olamine is the ethanolamine salt of the hydroxamic acidderivatve of piroctone.
Transparent antidandruff shampoos.
As a preservative and thickening agent in cosmetic preparations.In general, hair careformulations and used against seborrheic dermatitis