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Silver Sulfadiazine

Price 27000 INR/ Kilograms

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MOQ : 25 Kilograms

Silver Sulfadiazine Specification

HS Code
29350013

Molecular Formula
C10H9AgN4O2S

Ph Level
5.5-7.0.

Molecular Weight
357.14 Grams (g)

Particle Size
367 nm

Solubility
Freely soluble in 30% of ammonia solution; slightly soluble in acetone; practically insoluble in ethanol (95%), chloroform and ether.

Loss on Drying
0.18%

Smell
No Smell

Structural Formula
C10H9AgN4O2S

Boiling point
512.652.0 C at 760 mmHg

Melting Point
285

Storage
Room Temperature

Medicine Name
Silver Sulfadiazine

Chemical Name
Benzeneethanamine,4-amino-, hydrochloride (1:2) Superlist Name: 2-(4-Aminophenyl)ethylamine dihydrochloride

CAS No
13078-82-5

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Purity(%)
98%

Appearance
White to creamy-white, crystalline powder. Odorless to having a slight odor. Is Stable in air, but turns yellow on exposure to light.

Physical Form
Powder

Silver Sulfadiazine Trade Information

Minimum Order Quantity
25 Kilograms

Payment Terms
Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Cash in Advance (CID), Cash Advance (CA)

Supply Ability
1000 Kilograms Per Day

Delivery Time
7 Days

Packaging Details
DRUM

Main Export Market(s)
Western Europe, Central America, Eastern Europe, Middle East, South America, Australia, Asia, North America, Africa

Certifications
ISO ,GMP

About Silver Sulfadiazine

It is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns. We have gained huge fame amongst our customers as a trustworthy organization engaged in offering Silver Sulfadiazine. This drug has broad antimicrobial activity. It is bactericidal for many gram- negative and gram-positive bacteria as well as being effective against yeast. It is not a carbonic anhydrase inhibitor and may be useful in situations where such agents are contraindicated. It acts only on the cell membrane and cell wall to produce its bactericidal effect.

Silver Sulfadiazine Properties:

CAS Number: 13078-82-5
Name: Benzeneethanamine,4-amino-, hydrochloride (1: 2)
Superlist Name: 2-(4-Aminophenyl)ethylamine dihydrochloride
Formula: C₁₀H₉AgN₄O₂S
Molecular Weight: 209.12
Synonyms: p-amino-, dihydrochloride(7CI,8CI);4-(2-Aminoethyl)aniline dihydrochloride;Benzeneethanamine,4-amino-, dihydrochloride (9CI);4-Aminophenethylamine dihydrochloride;4-Aminobenzeneethanaminedihydrochloride;

How does it work

Patients with burn injuries are prescribed silver sulfadiazine together with other treatments to help prevent infection in their wound. An open wound can be infected with silver sulfadiazine since it prevents bacteria from growing. The bacteria are prevented from spreading throughout the skin or into the blood stream, causing a serious blood infection (sepsis). Silver sulfadiazine belongs to a class of drugs called sulfa antibiotics. Silver sulfadiazine should be avoided for premature babies and newborns between 2 months and one year of age due to the risk of serious side effects.

Applications Or where it is used

With second- and third-degree burns, silver sulfadiazine cream prevents and treats wound infections. In the event of severe burns or large areas of burns on the body, treatment in a hospital is required. Antibiotics such as silver sulfadiazine are used in treating bacterial infections. Bacteria are killed or prevented from growing by it

Manufacturing process

Silver sulfadiazine can be used in burn therapy if applied to the affected surface as a dispersion in a water-dispersible hydrophilic carrier.

An improved topical pharmaceutical composition for treating burns or microbial infections on humans or animals is provided. A pharmaceutical composition contains 0.1% - 1% w/w silver sulfadiazine as an antimicrobial drug and 0.2% w/w chlorhexidine gluconate as an antiseptic; silver sulfadiazine is nanonized.

How to use

Apply a thin layer of silver sulfadiazine (about 1/16 inch) to the affected areas. The medicine should always be applied to the affected areas. You must reapply this medicine if it has been washed off by moving around or by bathing, showering, or using a whirlpool bath.

Dosage of usage

Dosages of Silver Sulfadiazine:

Adult and Pediatric:

Cream

Burn wound infections (2nd degree/3rd degree)

Adult:

1% cream: apply daily every 12 hours to burn

Pediatric:

Infants under 2 months: contraindicated

Infants over 2 months (1% cream): Apply daily every 12 hours to burn

Side effects

Common side effects include:

Pain
Rash
Adverse nervous system effects
Acute kidney failure
Kidney swelling
Burning sensation
Cell death of the skin
Localized eruption of the skin
Transient skin discoloration
Destruction of red blood cells (in patients with G6PD deficiency)
Burning
Itching
Deficiency of granulocytes in the blood
Discontinued production of blood cells
Low blood platelet count
Low white blood cell count
Adverse gastrointestinal effects
Liver inflammation
Toxic injury to the liver
Presence of harmful bacteria via infection of a wound (sepsis)

Warnings and precautions while using this product

A silver sulfadiazine component is present in this medicine. When you are allergic to silver sulfadiazine or any of the other ingredients in this drug, you should not use Silvadene, Thermazene, or SSD Cream.

Keep out of the reach of children. Obtain medical attention or contact the Poison Control Center immediately if you overdose.

Contraindications

Sulfa allergy.
G6PD deficiency.
Hypersensitivity.
If you are pregnant or nursing near term, or the baby or infant is premature, or you are less than two months old, please avoid the use of suflanomides.

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