Sodium Valproate

About Sodium Valproate

It is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitu. We have set benchmarks of success in the market as a prominent organization engaged in offering Sodium Valproate. This drug belongs to the sulfonylurea class of insulin secretagogues. It increases both basal insulin secretion and meal-stimulated insulin release. Sodium Valproate is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications to control high blood sugar. It lowers blood sugar by causing the release of your body's natural insulin.

French drugmakers first marketed sodium valproate (valproate) as an anticonvulsant almost 50 years ago. Now it is the most prescribed antiepileptic drug worldwide due to its wide indications. Unfortunately, it has a number of potentially adverse effects.

Technical Specifications:

• CAS Number: 1069-66-5
• Name: Pentanoic acid,2-propyl-, sodium salt (1: 1)
• Superlist Name: Sodium 2-propylpentanoate
• Formula: C8H15NaO2
• Molecular Weight: 166.19
• Synonyms: Valpron;Vupral;2-Propylpentanoic acid sodium salt;Pentanoicacid, 2-propyl-, sodium salt (9CI);Valeric acid, 2-propyl-, sodium salt(7CI,8CI);Acediprol;Convulex;Depacon;Depakene;Depakene R; Epilim;KW 6066N;Micropakine LP;Orfiril;Selenica R;Sodium 2-propylpentanoate;Sodium2-propylvalerate;Sodium bispropylacetate;Sodium dipropylacetate;Sodiumvalproate; Depakene syrup8;Depakin;Depakine chronosphere;Dipropylacetate sodium;Sodium a,a-dipropylacetate;Valerin;Valproate sodium;
• EINECS: 213-961-8
• Melting Point: 300 °C
• Boiling Point: 220 °C at 760 mmHg
• Flash Point: 116.6 °C
• Solubility: water: 50 mg/mL
• Appearance: White solid
• Risk Codes: 22-61-36/38-36/37/38
• Safety: 36/37-53-45-37/39-26-36

How does it work?

A chemical in the brain called gamma-aminobutyric acid (GABA) is thought to reduce or prevent manic episodes when sodium valproate is taken. A calming effect is generated by GABA, which blocks nerve transmissions in the brain.

Applications Or where it is used:

Treatments for epilepsy and bipolar disorder include sodium valproate. Migraine headaches can also be treated with sodium valproate. This prescription medicine comes as a liquid, tablet, or capsule.

Manufacturing process:

Prescriptions are required for this medicine. It is available in the form of capsules, tablets, and a liquid. Granules are also available for mixing with food and drinks. Sodium valproate may also be administered as an injection, but this is usually only done in the hospital.

Side effects:

These and other serious adverse reactions are described in the labeling:

• Hepatic failure 
• Hyperammonemic encephalopathy 
• Bleeding and other hematopoietic disorders 
• Hypothermia 
• Birth defects 
• Decreased IQ following in utero 
• Pancreatitis 
• Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/Multiorgan hypersensitivity reactions 
• Somnolence in the elderly