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Acyclovir .

Price 4100.0 INR/ Kilograms

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MOQ : 25 Kilograms

Acyclovir . Specification

Shelf Life
3 Years

Solubility
Acyclovir is known for its poor water solubility, which affects its oral bioavailability and formulation development.

Loss on Drying
Not more than 6.0% (when dried at 105 C)

Structural Formula
C8H11N5O3

Heavy Metal (%)
NMT 20 ppm (parts per million)

Particle Size
Micronized Acyclovir: D90 (90% of particles): 10 50 m D50 (median particle size): ~5 20 m D10: ~1 5 m

Molecular Weight
225.21 Grams (g)

Melting Point
256.5 C (493.7 F)

Molecular Formula
C8H10N5NaO3

HS Code
29335990

Storage
Room Temperature

Medicine Name
Acyclovir

Chemical Name
2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one

CAS No
59277-89-3

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
Acyclovir is used to treat the symptoms of chickenpox, shingles, herpes virus infections of the genitals (sex organs), the skin, the brain, and mucous membranes (lips and mouth), and widespread herpes virus infections in newborns. Acyclovir is also used to prevent recurrent genital herpes infections.

Purity(%)
98%

Appearance
White crystalline powder

Physical Form
Liquid

Acyclovir . Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
Mumbai

Payment Terms
Cash Advance (CA), Cash in Advance (CID)

Supply Ability
1000 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
DRUM

Main Export Market(s)
Western Europe, Middle East, Africa, Asia, Australia, Central America, North America, South America, Eastern Europe

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Acyclovir .

We are offering high quality Acyclovir.We are known for manufacturing, exporting, distributing, trading and supplying Acyclovir in Gujarat, India. Further, this is safely packaged by our professionals in diverse packaging options that maintain its purity and effectiveness.

Shreeji Pharma International is leading Manufacturer, Exporter, Distributor, and Supplier of Bisacodyl Acyclovir in Gujarat. India. Shreeji Pharma International manufacturing & gmp; supplying all products under GMP site with all types of regulatory supports.

Shreeji Pharma International is the largest manufacturer, Exporter and supplier ofAcyclovir nowadays Shreeji Pharma International is one of the leading manufacturer and exporter, who is manufacturing Acyclovir as well as Intermediates of Acyclovir.

Shreeji Pharma International is exporter, supplier, distributor and manufacturers of the Active Pharmaceuticals Ingredients in many countries for many years.

Shreeji Pharma International currently export Bisacodyl to countries likeGulf Countries, South East Asia countries, African Countries, CIS Countries, LATAM countries, Central American Countries and in European countries.

Acyclovir Technical Description

1. General Information

Generic Name: Acyclovir

Brand Names: Zovirax, Sitavig, Acyclovir Sodium (for injection)

Drug Class: Antiviral (Antiherpetic)

ATC Code: J05AB01

Molecular Formula: CHNO

Molecular Weight: 225.21 g/mol

CAS Number: 59277-89-3

Chemical Structure:
Acyclovir is a synthetic purine nucleoside analog structurally related to guanine.

2. Chemical Structure & Properties

IUPAC Name:
2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one

LogP (Partition Coefficient): -1.56

Solubility:

Water: Slightly soluble (1.2 mg/mL at 25C)

pKa: 2.27 (acidic), 9.25 (basic)

Appearance: White crystalline powder

3. Mechanism of Action

Acyclovir is selectively phosphorylated by viral thymidine kinase to acyclovir monophosphate, which is then converted by host enzymes to the active acyclovir triphosphate. This compound inhibits viral DNA polymerase and incorporates into viral DNA, leading to chain termination during DNA replication.

4. Indications

Herpes Simplex Virus (HSV) types 1 and 2 mucocutaneous and genital infections

Varicella-Zoster Virus (VZV) including shingles (herpes zoster) and chickenpox

Prophylaxis in immunocompromised patients

HSV encephalitis

Neonatal herpes

5. Pharmacokinetics

Parameter	Oral Acyclovir	IV Acyclovir
Bioavailability	1020%	100%
Peak Plasma (Tmax)	1.52 hours	Rapid
Half-life (t)	2.53.3 hours (normal renal function)
Protein Binding	933%
Metabolism	Minimal (mostly excreted unchanged)
Excretion	Renal (glomerular filtration and tubular secretion)