Drotaverine Hcl PHARMA

About Drotaverine Hcl PHARMA

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Drotaverine Hydrochloride (HCl) is a pharmaceutical compound primarily used as a smooth muscle relaxant. It is commonly prescribed for the treatment of gastrointestinal, biliary, and urological spasms due to its antispasmodic properties.

Description:

Chemical Name: Drotaverine Hydrochloride

Molecular Formula: C21H24ClNO3

CAS Number: 74320-09-1

Appearance: Drotaverine Hydrochloride appears as a white to off-white crystalline powder that is odorless and soluble in water and alcohol.

Uses:

Drotaverine Hydrochloride is primarily used for:

Gastrointestinal Spasms: It is used to treat abdominal pain and discomfort caused by gastrointestinal spasms or conditions like irritable bowel syndrome (IBS).

Biliary Spasms: Drotaverine is effective in treating gallbladder-related spasms, often associated with conditions like biliary colic.

Urological Spasms: It is commonly used to relieve bladder spasms or renal colic caused by urinary tract issues, such as kidney stones.

Dysmenorrhea: Drotaverine is sometimes used to alleviate menstrual cramps caused by uterine contractions.

Dosage and Administration:

Oral Dosage: Drotaverine Hydrochloride is typically administered in tablet or capsule form for oral consumption.

Adult Dose: The standard dose is 40 mg to 80 mg taken 23 times daily, depending on the severity of the condition.

Maximum Dose: The usual maximum dose is 240 mg per day, but this should be determined by a healthcare provider based on individual needs.

Injectable Form: In some cases, intramuscular (IM) or intravenous (IV) injections may be prescribed for more severe cases, but this is typically done under medical supervision.

Typical Dose: 4080 mg once or twice daily.

Side Effects:

While Drotaverine Hydrochloride is generally well-tolerated, side effects can occur, including:

Dizziness: May cause dizziness or light-headedness, especially when standing up quickly.

Nausea or Vomiting: Gastrointestinal upset can occur in some individuals.

Skin Rash or Itching: Rare allergic reactions can cause a rash or itching.

Headache: Some individuals may experience mild headaches.

Hypotension: In rare cases, it may cause low blood pressure or a feeling of weakness.

Storage:

Storage Conditions: Drotaverine Hydrochloride should be stored in a cool, dry place, away from moisture and light. Tablets should be kept in their original container to protect from moisture.

Shelf Life: Typically, the shelf life of Drotaverine tablets or capsules is around 2 to 3 years, but always refer to the specific expiration date printed on the packaging.

Purity:

Purity: Pharmaceutical-grade Drotaverine Hydrochloride typically has a purity of 98%. It must meet the standards set by organizations such as the United States Pharmacopeia (USP) or the European Pharmacopoeia (EP).

Testing for Impurities: The substance is tested for impurities such as heavy metals, residual solvents, and other contaminants using high-performance techniques like HPLC