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Ofloxacin HCL Powder

Price 4000.0 INR/ Kilograms

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MOQ : 25 Kilograms, Kilograms

Ofloxacin HCL Powder Specification

Storage
Room Temperature

Shelf Life
3 Years

EINECS No
617-150-3

Solubility
Freely soluble (about 12 mg/mL at 25 C).

Molecular Formula
C H ClFN O

HS Code
2941.90.90

Melting Point
270 C to 273 C

Ph Level
3.5 to 5.5 for a 1% aqueous solution.

Molecular Weight
397.83 Kilograms (kg)

Heavy Metal (%)
Ofloxacin should be 20 ppm (parts per million).

Loss on Drying
not more than 0.20%.

Taste
Bitter

Particle Size
10 50 microns

Boiling point
not provided in the search results.

Smell
No Smell

Medicine Name
Floxin

Chemical Name
( )-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid hydrochloride

CAS No
82419-36-1

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
Uses of Ofloxacin HCL Ofloxacin HCL is used to treat a wide range of bacterial infections. It is a broad-spectrum fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication enzymes, leading to the death of the bacteria.

Purity(%)
98%

Appearance
White to pale yellow crystalline powder

Physical Form
Solid

Ofloxacin HCL Powder Trade Information

Minimum Order Quantity
25 Kilograms, Kilograms

FOB Port
Mumbai Port

Payment Terms
Cash Against Delivery (CAD), Cash Advance (CA), Cash in Advance (CID), Delivery Point (DP), Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Letter of Credit (L/C)

Supply Ability
100 Kilograms, Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
Drum Packing

Main Export Market(s)
Middle East, Africa, Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Ofloxacin HCL Powder

It is a synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. We have earned worldwide acknowledgment as one of the leading organizations engaged in offering Ofloxacin. This medication is used to treat a variety of bacterial infections. It belongs to a class of drugs called quinolone antibiotics. Ofloxacin works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections such as common cold and flu. This drug is active against both Gram-positive and Gram-negative bacteria.

Ofloxacin HCL Powder is a pharmaceutical raw material that contains the hydrochloride salt of Of loxacin, a broad-spectrum synthetic fluoroquinolone antibiotic. It is primarily used in the formulation of oral tablets, ophthalmic solutions, and topical treatments. Here's a detailed overview:

1. Chemical Profile

Chemical Name: Ofloxacin hydrochloride
Molecular Formula: C18H20FN3O4 HCl
Molecular Weight: 385.83 g/mol (base); 421.8 g/mol (HCl salt)
Appearance: White to pale yellow crystalline powder
Solubility: Soluble in water, slightly soluble in ethanol and methanol
pH (1% solution): Typically between 3.5 and 5.5

2. Mechanism of Action

Of loxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This leads to bacterial cell death, making it bactericidal.

3. Spectrum of Activity

Effective against:

Gram-positive bacteria: Staphylococcus aureus, Streptococcus pneumoniae
Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Haemophilus influenzae
Atypicals: Mycoplasma, Chlamydia

4. Pharmaceutical Uses

Ofloxacin HCL powder is used in the manufacture of:

Oral tablets and capsules
Eye/ear drops
Topical creams or ointments
Injectables (less common)

5. Dosage Forms and Strengths

Tablets: Commonly 200 mg, 300 mg, or 400 mg
Eye Drops: Usually 0.3% solution
Topical Creams: Typically 0.3% or as directed

6. Stability and Storage

Store in a cool, dry place (below 25C)
Protect from light and moisture
Shelf life: 2 to 3 years, depending on packaging and storage

7. Safety and Handling

Hazards: May cause skin/eye irritation. Inhalation of dust should be avoided.
Protective equipment: Gloves, masks, and eye protection recommended during handling.
MSDS: Always refer to the Material Safety Data Sheet for detailed hazard and first-aid information.