Theophylline .

Price 840.0 INR/ Kilograms

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MOQ : 25 Kilograms

Theophylline . Specification

Ph Level
7.0 to 9.0

Taste
Odorless

Heavy Metal (%)
10 ppm

Storage
Room Temperature

Loss on Drying
less than 1.0%

Smell
No Smell

Molecular Formula
C7H8N4O2

Melting Point
271 273 C

Molecular Weight
180.164 Grams (g)

Shelf Life
3 Years

Solubility
Soluble in water and alcohol

EINECS No
200-366-3

Medicine Name
Theophylline

Chemical Name
3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione

CAS No
58-55-9

Type
Pharmaceutical Intermediates

Grade
Medicine Grade

Usage
Theophylline is primarily used in the treatment of respiratory conditions, particularly those involving bronchoconstriction. Here are the main uses: 1. Asthma: Theophylline is used as a bronchodilator to relieve symptoms of asthma, particularly for chronic asthma or when other treatments are not sufficient. It works by relaxing the muscles around the airways, making it easier to breathe. Long-term management: It is generally used for maintenance therapy in asthma, particularly in combination with other medications like inhaled corticosteroids. 2. Chronic Obstructive Pulmonary Disease (COPD): Theophylline is used to relieve symptoms of COPD (including chronic bronchitis and emphysema), such as shortness of breath and wheezing. It improves airflow by dilating the airways and helping to clear mucus. 3. Apnea of Prematurity (in Neonates): Theophylline is used in premature infants to treat apnea of prematurity. This is a condition where premature infants stop breathing for short periods. Theophylline helps stimulate respiratory drive and improves breathing patterns in neonates. 4. Chronic Bronchitis: Chronic bronchitis, often associated with COPD, is a condition where the airways are inflamed and narrowed. Theophylline helps dilate the airways and ease breathing. 5. Other Off-Label Uses: Theophylline may sometimes be used for other respiratory conditions, including pulmonary fibrosis or interstitial lung diseases, though it's less common today with newer medications available. Dosage and Administration: Oral Tablets: Theophylline is often given in extended-release form for once or twice-daily dosing. Injectable Form: For emergency situations or severe exacerbations of respiratory conditions. Oral Syrups or Solutions: For children or those who have difficulty swallowing tablets. Precautions: Narrow Therapeutic Range: Theophylline has a narrow therapeutic window, meaning the difference between a therapeutic dose and a toxic dose is small. Blood levels must be monitored regularly to avoid toxicity. Side Effects: Common side effects include insomnia, headaches, nausea, vomiting, and heart palpitations. High levels can lead to arrhythmias and seizures. Interactions: Theophylline interacts with several other medications, including certain antibiotics (like ciprofloxacin), antidepressants, and anticonvulsants, affecting its metabolism. Mechanism of Action: Theophylline works by inhibiting phosphodiesterase enzymes, leading to increased levels of cyclic AMP (cAMP), which relaxes the smooth muscles of the airways and opens up the air passages, making it easier to breathe.

Purity(%)
98%

Appearance
White to off-white crystalline powder

Physical Form
Liquid

Theophylline . Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
Mumbai

Payment Terms
Cash Advance (CA), Cash in Advance (CID)

Supply Ability
1000 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
25kgs

Main Export Market(s)
Eastern Europe, Middle East, Africa, Asia, Australia, Central America, North America, South America, Western Europe

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Theophylline .

It is a methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. We are a fast-paced organization, committed to meet the rising needs of our valuable clients by offering Theophylline. It acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. This medication is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema). It must be used regularly to prevent wheezing and shortness of breath. Theophylline belongs to a class of drugs known as xanthines.

Features:

Product Name : Theophylline
Chemical Names : 1,3-Dimethylxanthine; Elixophyllin; Theophyllin; Theolair; Nuelin; Theophylline anhydrous; Respbid; Theocin; Theo-dur; Elixophylline; Pseudotheophylline; Lanophyllin; Theovent; Uniphyl; Slo-phyllin; Accurbron; Armophylline; Bronkodyl; Doraphyllin; Liquophylline; Maphylline; Medaphyllin; Optiphyllin; Parkophyllin; Teofyllamin; Theacitin; Theocontin
Molecular Formula : C₇H₈N₄O₂
Molecular Weight : 180.167 g/mol
IUPAC Name : 1,3-dimethyl-7H-purine-2,6-dione
CAS Number : 58-55-9
Physical Description : White crystalline powder
Color : White
Odor : Odorless
Taste : Bitter
Melting Point : 270-274C
Solubility : Slightly soluble in water, ethanol, ether, chloroform
Stability : Stable under recommended storage conditions.