Cellulose Acetate Phthalate

1800 INR/Kilograms

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Product Details:

Taste Odorless
Molecular Weight 678.58992 Grams (g)
Moisture (%) not available
Storage Room Temperature
Loss on Drying 5.0 %
Ph Level not available
Assay not available
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Cellulose Acetate Phthalate Price And Quantity

Price 1800 INR/Kilograms
Minimum Order Quantity 25 Kilograms
Price Range 1500.00 - 1800.00 INR/Kilograms

Cellulose Acetate Phthalate Product Specifications

EINECS No not available
Shelf Life 9 Days
Water Solubility insoluble in water
Usage It is used as an enteric film-coating material, as a microencapsulation agent, or as a matrix binder for tablets and capsules
Assay not available
Ph Level not available
HS Code 39121190
Molecular Formula C28H38O19
Loss on Drying 5.0 %
Grade medicine grade
Heavy Metal (%) < 10
Structural Formula C28H38O19
Storage Room Temperature
Appearance White or off-white powder
Smell No Smell
Application Cellulose acetate phthalate is commonly applied to solid-dosage forms either by coating from organic or aqueous solvent systems, or by direct compression.
Purity(%) 99%
Chemical Name cellulose acetate hydrogen
CAS No 9004-38-0
Moisture (%) not available
Molecular Weight 678.58992 Grams (g)
Taste Odorless

Cellulose Acetate Phthalate Trade Information

FOB Port mumbai
Payment Terms Letter of Credit (L/C) Cash Against Delivery (CAD) Delivery Point (DP) Letter of Credit at Sight (Sight L/C) Days after Acceptance (DA) Cash in Advance (CID) Cash Advance (CA)
Supply Ability 100 Kilograms Per Day
Delivery Time 7 Days
Sample Available Yes
Sample Policy Free samples are available
Packaging Details DRUM PACK
Main Export Market(s) Asia Australia South America Western Europe Middle East Central America Eastern Europe North America Africa
Main Domestic Market All India
Certifications ISO / GMP

Product Description

Cellulose acetate phthalate is a high-quality product that we offer. As a manufacturer, exporter, distributor, trader, and supplier of Cellulose Acrylate Phthalate, we serve clients all over India as well as African Countries, CIS Countries, LATAM countries, Gulf Countries, South East Asia countries, Central American Countries and European countries. Our professionals ensure the purity and effectiveness of this product by packing it according to diverse packaging options.

Cellulose Acetate Phthalate Properties:

Synonyms: Aquateric
CAS NO.: 9004-38-0
EINECS: 618-382-8
Molecular Weight: 678.58992
Molecular Formula: C₂₈H₃₈O₁₉
Appearance: White or off-white powder

Introduction of product:

Also known as known as cellacefate (INN) and cellulosi acetas phthalas, cellulose acetate phthalate (CAP), is a polymer phthalate commonly used in pharmaceutical formulations, such as enteric coating for tablets and capsules and in controlled release formulations. It can be dissolved in buffer solutions with pH values as low as 6. Consequently, it has found use in enteric coatings. Adding plasticizers makes the ester more water-resistant.

How does it work:

Cellulose acetate phthalate can be used in many ways, for instance as a microencapsulation agent, as an enteric film-coating material, or as a matrix binder for tablets and capsules. They won't dissolve under mildly acidic conditions in the intestine, but will dissolve in strongly acidic gastric fluid. Acetic acid, acetone, and pyridine are some of the organic solvents commonly used in the phthaloylation of cellulose acetate. Anhydrous sodium acetate is one of the basic catalysts used when using acetic acid, amines is another when using acetone, and the organic solvent as well when using pyridine as reaction medium.

Applications Or where it is used:

The cellulose acetate phthalate (CAP) material is used for enteric coatings or as a matrix binder for tablets and capsules. Surface coatings such as these resist contact with highly acidic gastric fluids, but dissolve in mildly acidic or neutral intestinal environments.

Cellulose acetate phthalate is applied to solid-dosage forms by two, one by by coating from organic or aqueous solvent systems, and other by direct compression. Concentrations generally range from 0.5 to 9.0% of the core weight. Plasticizers improve the water resistance of this coating material. Formulations using plasticizers outperform its formulations alone.

It is compatible with many plasticizers, such as:

Acetylated monoglyceride
Butyl phthalybutyl glycolate
Dibutyl tartrate
Diethyl phthalate
Dimethyl phthalate
Ethyl phthalylethyl glycolate
Glycerin; propylene glycol
Triacetin
Triacetin citrate
Tripropionin

The compound can also be used as part of another coating agent, such as cellulose, in preparations for controlled-release drugs.

In terms of therapeutic application, cellulose acetate phthalate recently demonstrated experimental microbicidal activity against sexually transmitted disease pathogens, such as the HIV-1 retrovirus.

Manufacturing process:

Wood pulp is converted into cellulose acetate by reaction with acetic acid and acetic anhydride in the presence of sulfuric acid. Hydrolysis of the triacetate is then carried out to achieve the desired substitution level.