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Cellulose Acetate Phthalate

Price 1800.0 INR/ Kilograms

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MOQ : 25 Kilograms

Cellulose Acetate Phthalate Specification

Heavy Metal (%)
< 10

Ph Level
not available

Structural Formula
C28H38O19

Moisture (%)
not available

Smell
No Smell

Molecular Formula
C28H38O19

Assay
not available

Storage
Room Temperature

Molecular Weight
678.58992 Grams (g)

Water Solubility
insoluble in water

Taste
Odorless

HS Code
39121190

Shelf Life
9 Days

Loss on Drying
5.0 %

Appearance
White or off-white powder

Grade
medicine grade

EINECS No
not available

Chemical Name
cellulose acetate hydrogen

CAS No
9004-38-0

Usage
It is used as an enteric film-coating material, as a microencapsulation agent, or as a matrix binder for tablets and capsules

Purity(%)
99%

Application
Cellulose acetate phthalate is commonly applied to solid-dosage forms either by coating from organic or aqueous solvent systems, or by direct compression.

Cellulose Acetate Phthalate Trade Information

Minimum Order Quantity
25 Kilograms

FOB Port
mumbai

Payment Terms
Cash Against Delivery (CAD), Cash Advance (CA), Cash in Advance (CID), Days after Acceptance (DA), Delivery Point (DP), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)

Supply Ability
100 Kilograms Per Day

Delivery Time
7 Days

Sample Available
No

Sample Policy
Free samples are available

Packaging Details
DRUM and bag packing

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Certifications
WE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED

About Cellulose Acetate Phthalate

Cellulose acetate phthalate is a high-quality product that we offer. As a manufacturer, exporter, distributor, trader, and supplier of Cellulose Acrylate Phthalate, we serve clients all over India as well as African Countries, CIS Countries, LATAM countries, Gulf Countries, South East Asia countries, Central American Countries and European countries. Our professionals ensure the purity and effectiveness of this product by packing it according to diverse packaging options.

Cellulose Acetate Phthalate Properties:

Synonyms: Aquateric
CAS NO.: 9004-38-0
EINECS: 618-382-8
Molecular Weight: 678.58992
Molecular Formula: C₂₈H₃₈O₁₉
Appearance: White or off-white powder

Introduction of product:

Also known as known as cellacefate (INN) and cellulosi acetas phthalas, cellulose acetate phthalate (CAP), is a polymer phthalate commonly used in pharmaceutical formulations, such as enteric coating for tablets and capsules and in controlled release formulations. It can be dissolved in buffer solutions with pH values as low as 6. Consequently, it has found use in enteric coatings. Adding plasticizers makes the ester more water-resistant.

How does it work:

Cellulose acetate phthalate can be used in many ways, for instance as a microencapsulation agent, as an enteric film-coating material, or as a matrix binder for tablets and capsules. They won't dissolve under mildly acidic conditions in the intestine, but will dissolve in strongly acidic gastric fluid. Acetic acid, acetone, and pyridine are some of the organic solvents commonly used in the phthaloylation of cellulose acetate. Anhydrous sodium acetate is one of the basic catalysts used when using acetic acid, amines is another when using acetone, and the organic solvent as well when using pyridine as reaction medium.

Applications Or where it is used:

The cellulose acetate phthalate (CAP) material is used for enteric coatings or as a matrix binder for tablets and capsules. Surface coatings such as these resist contact with highly acidic gastric fluids, but dissolve in mildly acidic or neutral intestinal environments.

Cellulose acetate phthalate is applied to solid-dosage forms by two, one by by coating from organic or aqueous solvent systems, and other by direct compression. Concentrations generally range from 0.5 to 9.0% of the core weight. Plasticizers improve the water resistance of this coating material. Formulations using plasticizers outperform its formulations alone.

It is compatible with many plasticizers, such as:

Acetylated monoglyceride
Butyl phthalybutyl glycolate
Dibutyl tartrate
Diethyl phthalate
Dimethyl phthalate
Ethyl phthalylethyl glycolate
Glycerin; propylene glycol
Triacetin
Triacetin citrate
Tripropionin

The compound can also be used as part of another coating agent, such as cellulose, in preparations for controlled-release drugs.

In terms of therapeutic application, cellulose acetate phthalate recently demonstrated experimental microbicidal activity against sexually transmitted disease pathogens, such as the HIV-1 retrovirus.

Manufacturing process:

Wood pulp is converted into cellulose acetate by reaction with acetic acid and acetic anhydride in the presence of sulfuric acid. Hydrolysis of the triacetate is then carried out to achieve the desired substitution level.

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