Calcium levulinate

Product Description

General Description:

Calcium Levulinate is a calcium salt of levulinic acid, primarily used as a calcium supplement in pharmaceutical applications. It helps correct or prevent calcium deficiency in the body, particularly when oral administration is not effective or rapid correction is needed.

• Chemical Name: Calcium 4-oxopentanoate

• Molecular Formula: CHCaO

• Molecular Weight: 270.29 g/mol

• CAS Number: 5785-44-4

• EINECS Number: 227-391-9

Appearance:

• Form: Crystalline powder or granules

• Color: White to off-white

• Solubility: Soluble in water, slightly soluble in alcohol

• Odor: Odorless

Pharmaceutical Use:

Calcium levulinate is used in:

• Treatment of hypocalcemia (low blood calcium levels)

• Calcium supplementation when oral intake is insufficient

• Parenteral therapy (e.g., IV or IM injection) in hospital settings

It is often preferred over calcium gluconate or calcium chloride in certain patients because it may cause less irritation at the injection site.

Mechanism of Action:

Calcium is essential for:

• Neuromuscular function

• Cardiac activity

• Blood coagulation

• Bone formation

Calcium levulinate increases serum calcium levels by providing ionized calcium directly into the bloodstream when administered intravenously or intramuscularly.

Storage and Handling:

• Storage: Store in a cool, dry place, protected from moisture and light.

• Stability: Stable under normal conditions, but sensitive to heat and humidity.

Precautions:

• Avoid in hypercalcemia or severe kidney dysfunction

• Monitor serum calcium and renal function during therapy

• May cause injection site pain, nausea, or hypercalcemia with overuse